Protein Information

Name glutamine synthetase
Synonyms GLNS; GLUL; GS; Glutamate ammonia ligase; Glutamate ammonia ligase; Glutamine synthase; Glutamine synthetase; PIG43…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
9252090 Tygstrup N, Jensen SA, Krog B, Dalhoff K: Expression of liver functions following sub-lethal and non-lethal doses of allyl alcohol and acetaminophen in the rat. J Hepatol. 1997 Jul;27(1):156-62.

The mRNA of glutamine synthetase was significantly more reduced by acetaminophen than by allyl alcohol.
81(1,1,1,1) Details
7905753 Kress S, Katz N: Discrimination between periportal and pericentral necrosis of rat liver by determination of glutamine synthetase and other enzyme activities in serum. Eur J Clin Chem Clin Biochem. 1993 Nov;31(11):733-8.

Periportal or pericentral necrosis of rat liver was produced by injection of allyl-alcohol or bromobenzene, respectively.
3(0,0,0,3) Details
2835185 Penttila KE: Allyl alcohol cytotoxicity and glutathione depletion in isolated periportal and perivenous rat hepatocytes. Chem Biol Interact. 1988;65(2):107-21.

The distinct origin of the cell preparations was confirmed by the p.p./p.v. ratios of alanine aminotransferase (p.p./p.v. = 1.8), lactate dehydrogenase (1.3) and glutamine synthetase (0.10).
1(0,0,0,1) Details