Protein Information

Name transferase
Synonyms 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
10642611 York WS, Hawkins R: Preparation of oligomeric beta-glycosides from cellulose and hemicellulosic polysaccharides via the glycosyl transferase activity of a trichoderma reesei cellulase. Glycobiology. 2000 Feb;10(2):193-201.

A polymeric donor substrate (xyloglucan or cellulose) was incubated with the enzyme in an aqueous solution containing 20% of the acceptor alcohol (allyl alcohol, glycerol, ethanol, ethylene glycol, and methanol, respectively).
1(0,0,0,1) Details
8216823 Virtanen P, Lassila V, Soderstrom KO: Protoberberine alkaloids from Enantia chlorantha therapy of allyl-alcohol- and D-galactosamine-traumatized rats. Pathobiology. 1993;61(1):51-6.

There was a significant increase in serum alanine transferase (ALT) and serum alkaline phosphatase (APHOS) values induced by AA traumatization, which were lowered following Hepasor treatment.
1(0,0,0,1) Details
15940471 Anand SS, Mumtaz MM, Mehendale HM: Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats. Arch Toxicol. 2005 Nov;79(11):671-82. Epub 2005 Jun 7.

Liver injury was assessed by plasma alanine amino transferase (ALT) activity and liver tissue repair was measured by (3) H-thymidine incorporation into hepatonuclear DNA.
1(0,0,0,1) Details
2741658 Virtanen P, Lassila V, Njimi T, Mengata DE: Effect of splenectomy on hepasor treatment in allyl-alcohol-traumatized rat liver. Acta Anat. 1989;134(4):301-4.

Biochemical assays from blood plasma, serum alanine transferase, serum alkaline phosphatase, serum creatinine, serum hydroxyproline and serum calcium were done and the total amount of blood obtained by decapitation was measured.
1(0,0,0,1) Details
3977950 Poulsen HE, Lerche A, Pedersen NT: Potentiated hepatotoxicity from concurrent administration of acetaminophen and allyl alcohol to rats. Biochem Pharmacol. 1985 Mar 15;34(6):727-31.

Plasma alanine transferase activity was elevated more and earlier after treatment with acetaminophen and allyl alcohol compared to administration of acetaminophen alone.
6(0,0,1,1) Details
3377801 Haenen GR, Vermeulen NP, Tai Tin Tsoi JN, Ragetli HM, Timmerman H, Blast A: Activation of the microsomal glutathione-S-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein. Biochem Pharmacol. 1988 May 15;37(10):1933-8.

Allyl alcohol is hepatotoxic.
The effect of acrolein in vitro and in vivo on the glutathione (GSH) dependent protection of liver microsomes against lipid peroxidation, and on the microsomal GSH-S-transferase (GSH-tr) in the rat was determined.
1(0,0,0,1) Details