| Name | cyclooxygenase 2 |
|---|---|
| Synonyms | COX 2; COX2; PHS2; PGG/HS; Cyclooxygenase 2; Cyclooxygenase 2b; Cycloxygenase 2; PGH synthase 2… |
| Name | allyl alcohol |
|---|---|
| CAS | 2-propen-1-ol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11446826 | Ganey PE, Barton YW, Kinser S, Sneed RA, Barton CC, Roth RA: Involvement of cyclooxygenase-2 in the potentiation of allyl alcohol-induced liver injury by bacterial lipopolysaccharide. Toxicol Appl Pharmacol. 2001 Jul 15;174(2):113-21. Upregulation of cyclooxygenase-2 (COX-2) and production of eicosanoids are important aspects of inflammation, therefore studies were undertaken to investigate the role of COX-2 in LPS-induced enhancement of liver injury from allyl alcohol. |
37(0,1,2,2) | Details |
| 14657518 | Maddox JF, Domzalski AC, Roth RA, Ganey PE: 15-deoxy enhances allyl alcohol-induced toxicity in rat hepatocytes. Toxicol Sci. 2004 Feb;77(2):290-8. Epub 2003 Dec 2. Allyl alcohol causes hepatotoxicity that is potentiated by small doses of bacterial lipopolysaccharide (LPS) through a cyclooxygenase-2 (COX-2)-dependent mechanism. |
31(0,1,1,1) | Details |