| Name | mitogen activated protein kinase (protein family or complex) |
|---|---|
| Synonyms | MAPK; mitogen activated protein kinase; mitogen activated protein kinases |
| Name | OCH |
|---|---|
| CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17142672 | Lacchini AH, Davies AJ, Mackintosh D, Walker AJ: Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation. J Exp Biol. 2006 Dec;209(Pt 24):4829-40. Moreover, extracellular signal-regulated kinase (ERK) was found to be a downstream target of molluscan PKC, operating via a MAPK/ERK kinase (MEK)-dependent mechanism. |
1(0,0,0,1) | Details |
| 16522737 | Orihuela PA, Parada-Bustamante A, Zuniga LM, Croxatto HB: Inositol triphosphate participates in an nongenomic signalling pathway involved in accelerated oviductal transport in cycling rats. J Endocrinol. 2006 Mar;188(3):579-88. Here we examined the role of the inositol (IP3) and mitogen-activated protein kinase (MAPK) signalling cascades in this nongenomic pathway. |
4(0,0,0,4) | Details |
| 12402303 | Ruiter GA, Verheij M, Zerp SF, Moolenaar WH, Van Blitterswijk WJ: Submicromolar doses of alkyl-lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 cells. Int J Cancer. 2002 Dec 1;102(4):343-50. We previously reported that ALPs, when added at micromolar concentrations (5-25 microM), inhibit growth factor-induced MAPK/ERK activation and enhance radiation-induced apoptosis. |
2(0,0,0,2) | Details |
| 10679516 | Ito T, Kozawa O, Tanabe K, Niwa M, Matsuno H, Sakai N, Ito H, Kato K, Uematsu T: p38 MAP kinase is required for -stimulated HSP27 induction in aortic smooth muscle cells. Hypertension. 2000 Feb;35(2):673-8. In the present study, we examined whether the mitogen-activated protein (MAP) kinase superfamily is involved in the AVP-stimulated HSP27 induction in A10 cells. |
1(0,0,0,1) | Details |
| 18804531 | Eisinger DA, Ammer H: Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases. Cell Signal. 2008 Dec;20(12):2324-31. Epub 2008 Sep 5. Together, these data describe an alternative ERK1/2 signaling pathway in which the DOR transactivates the growth factor receptor associated mitogen-activated protein kinase cascade in an integrin-dependent manner. |
1(0,0,0,1) | Details |
| 12660222 | Maccarrone M, Battista N, Meloni M, Bari M, Galleri G, Pippia P, Cogoli A, Finazzi-Agro A: Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release. J Leukoc Biol. 2003 Apr;73(4):472-81. The intracellular chelator EGTA-acetoxymethylester reduced 5-LOX activity and apoptosis to 30-40% of controls, whereas the p38 mitogen-activated protein kinase inhibitor SB203580 was ineffective. |
1(0,0,0,1) | Details |