| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | OCH |
|---|---|
| CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14602912 | Dorner S, Panuschka C, Schmid W, Barta A: Mononucleotide derivatives as ribosomal P-site substrates reveal an important contribution of the 2'-OH to activity. Nucleic Acids Res. 2003 Nov 15;31(22):6536-42. A model is discussed how further interactions of the 2'-OH in the transition state might influence peptidyl transferase activity. |
1(0,0,0,1) | Details |
| 11328763 | Lira R, Contreras LM, Rita RM, Urbina JA: Mechanism of action of anti-proliferative lysophospholipid analogues against the protozoan parasite Trypanosoma cruzi: potentiation of in vitro activity by the sterol biosynthesis inhibitor ketoconazole. J Antimicrob Chemother. 2001 May;47(5):537-46. Antiproliferative synergism was observed as a consequence of combined treatment of epimastigotes with ET-18-OCH (3) and ketoconazole, a sterol biosynthesis inhibitor, probably due to the fact that a secondary effect of the latter is also a blockade of PC synthesis at the level of PE-PC-N-methyl-transferase. |
1(0,0,0,1) | Details |
| 18008069 | Cui H, Shen J, Lu D, Zhang T, Zhang W, Sun D, Wang PG: 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer Chemother Pharmacol. 2008 Aug;62(3):509-15. Epub 2007 Nov 16. PURPOSE: The over-expression of S-transferase Pi (GSTpi) in tumors and inhibitory effect of GSTpi to JNK are two possible causes of the development of drug-resistance in chemotherapy. |
1(0,0,0,1) | Details |