Protein Information

Name adenylate cyclase
Synonyms AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC…

Compound Information

Name OCH
CAS 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
12972400 Son M, Ito Y, Sato S, Ishikawa T, Kondo M, Nakayama S, Shimokata K, Kume H: Apical and basolateral ATP-induced anion secretion in polarized human airway epithelia. Am J Respir Cell Mol Biol. 2004 Mar;30(3):411-9. Epub 2003 Sep 11.


Antagonists of phosphatidylinositol-phospholipase C (U73122, ET-18-OCH (3)) were without any effect on the bilateral ATP-induced I (sc), which were, in contrast, attenuated by a phosphatidylcholine-phospholipase C inhibitor (D609) and an adenylate cyclase inhibitor (SQ22536).
2(0,0,0,2) Details
10860858 Kane JK, Tanaka H, Parker SL, Yanagisawa M, Li MD: Sensitivity of orexin-A binding to phospholipase C inhibitors, neuropeptide Y, and secretin. Biochem Biophys Res Commun. 2000 Jun 16;272(3):959-65.


Among secretin-related peptides, the rank order of potency was porcine secretin > or = orexin-A > human pituitary adenylate cyclase-activating peptide > orexin-B > porcine vasoactive intestinal peptide.
1(0,0,0,1) Details