| 18008069 |
Cui H, Shen J, Lu D, Zhang T, Zhang W, Sun D, Wang PG: 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer Chemother Pharmacol. 2008 Aug;62(3):509-15. Epub 2007 Nov 16.
GST activity was measured with spectrophotometry using 1-chlro-2,4-dinitrobenzene (CDNB) and GSH as substrates. (omit "Apoptosis was evaluated by annexin V staining and flow cytometry"). c-Jun N-terminal kinase 1 (JNK1) association with GSTpi and activation of c-Jun were evaluated with immunoprecipitation and western blot. |
4(0,0,0,4) |
Details |
| 10679516 |
Ito T, Kozawa O, Tanabe K, Niwa M, Matsuno H, Sakai N, Ito H, Kato K, Uematsu T: p38 MAP kinase is required for vasopressin-stimulated HSP27 induction in aortic smooth muscle cells. Hypertension. 2000 Feb;35(2):673-8.
On the contrary, AVP had little effect on SAPK (stress-activated protein kinase)/JNK (c-Jun N-terminal kinase) phosphorylation. |
1(0,0,0,1) |
Details |