| 19244550 |
Mollinedo F, Gajate C, Morales AI, del Canto-Janez E, Justies N, Collia F, Rivas JV, Modolell M, Iglesias A: Novel anti-inflammatory action of edelfosine lacking toxicity with protective effect in experimental colitis. J Pharmacol Exp Ther. 2009 May;329(2):439-49. Epub 2009 Feb 25.
Because L-selectin locates in lipid rafts and plays a crucial role in the recruitment of leukocytes into inflamed tissues, we hypothesized that edelfosine might affect inflammation by modulating L-selectin and inflammatory cell migration. |
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