Protein Information

Name lactate dehydrogenase (protein family or complex)
Synonyms LDH; lactate dehydrogenase; lactate dehydrogenases

Compound Information

Name trichlorfon
CAS

Reference List

PubMed Abstract RScore(About this table)
516603 Bogatykh TA, Orlova NV, Kuznetsova TV: [Activity of lactate dehydrogenase and glucose-6-phosphate dehydrogenase activity in rat testicular tissues after exposure to certain pesticides]. Vopr Pitan. 1979 Sep-Oct;(5):49-53.

3(0,0,0,3) Details
1475794 Yamano T, Morita S: Hepatotoxicity of trichlorfon and dichlorvos in isolated rat hepatocytes. . Toxicology. 1992 Nov 22;76(1):69-77.

These compounds produced toxic effects on hepatocytes as evidenced by malondialdehyde production and lactate dehydrogenase leakage in a dose-dependent manner up to the concentration of 2 mM, dichlorvos being more toxic than trichlorfon.
31(0,1,1,1) Details
6784341 Mukhamedzhanov EK, Apsatarova RA, Ionina MP: [Effect of organophosphate pesticides on oxidative metabolism against a background of a protein-balanced and -imbalanced diet]. Vopr Pitan. 1981 Jan-Feb;(1):56-60.


The animals who had received low-grade gluten protein demonstrated, in the course of injections of organophosphorous pesticides, a considerable activation of glycolytic enzymes (aldolase and lactate dehydrogenase--LDH), changes in the spectra of LDH isozymes and an increase in the activity of a non-precipitated fraction of dehydrogenases belonging to the tricarboxylic acid series.
1(0,0,0,1) Details