Protein Information

Name kinesin
Synonyms KIF5C; KIF5A; NKHC; KINN; Kinesin family member 5C; Kinesin heavy chain isoform 5C; Kinesin heavy chain neuron specific 2; NKHC 2…

Compound Information

Name oryzalin
CAS 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide

Reference List

PubMed Abstract RScore(About this table)
16945151 Peters NT, Kropf DL: Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes. BMC Plant Biol. 2006 Aug 31;6:19.

5(0,0,0,5) Details
17957256 Yang G, Gao P, Zhang H, Huang S, Zheng ZL: A mutation in MRH2 kinesin enhances the root hair tip growth defect caused by constitutively activated ROP2 small GTPase in Arabidopsis. PLoS One. 2007 Oct 24;2(10):e1074.

Consistently, the MT-stabilizing drug taxol could partially rescue the wavy root hair phenotype of mrh2-3, and the MT-depolymerizing drug Oryzalin slightly enhanced the root hair tip growth defect in CA1-1.
3(0,0,0,3) Details
10760237 Mathur J, Chua NH: Microtubule stabilization leads to growth reorientation in Arabidopsis trichomes. Plant Cell. 2000 Apr;12(4):465-77.


Taxol-induced microtubule stabilization also led to the initiation of new branch points in the zwichel mutant of Arabidopsis, which is defective in a kinesin-like microtubule motor protein and possesses trichomes that are less branched.
1(0,0,0,1) Details