Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name isocarbophos
CAS 1-methylethyl 2-[[amino(methoxy)phosphinothioyl]oxy]benzoate

Reference List

PubMed Abstract RScore(About this table)
16824333 Liu L, Xie GY, Wang J, Sun JX: [Experimental study on protective effects of HupA in the treatment of isocarbophos poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 Jun;24(6):323-5.

OBJECTIVE: To investigate the therapeutic and prophylactic efficiency of HupA in mice with acute isocarbophos poisoning, and the protective effects of the HupA on AChE inhibited by isocarbophos.
180(2,2,5,5) Details
14694590 Ju Z, Sun J: [The neuromuscular transmission effects induced by pralidoxine chloride on rats with acute isocarbophos poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2002 Dec;20(6):425-6.

CONCLUSION: PAM-Cl has "non-AChE-reactivating effects", it could markedly improve isocarbophos-induced NMT block of gastrocnemius.
37(0,1,2,2) Details