Protein Information

Name melanoma antigen
Synonyms Melanoma antigen

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
7688577 Toporowicz A, Gersten DM, Hearing VJ, Brown WE, Vlock DR: Cross-reactivity between murine melanoma antigen B700 and a human melanoma-associated antigen (M-66) recognized by autologous antibody: evidence suggesting shared epitopes. Biochim Biophys Acta. 1993 Aug 4;1182(1):51-6.

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9176405 Chi DD, Merchant RE, Rand R, Conrad AJ, Garrison D, Turner R, Morton DL, Hoon DS: Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas. Am J Pathol. 1997 Jun;150(6):2143-52.


The MAAs studied included tyrosinase (Tyr), tyrosinase-related protein-1 and -2 (TRP-1 and TRP-2), gp100, human melanoma antigen-encoding genes 1 and 3 (MAGE-1 and MAGE-3), and melanotransferrin (p97).
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16227204 Chang CC, Hernandez-Guzman FG, Luo W, Wang X, Ferrone S, Ghosh D: Structural basis of antigen mimicry in a clinically relevant melanoma antigen system. J Biol Chem. 2005 Dec 16;280(50):41546-52. Epub 2005 Oct 14.

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12755292 Catchpole B, Gould SM, Kellett-Gregory LM, Dobson JM: Development of a multiple-marker polymerase chain reaction assay for detection of metastatic melanoma in lymph node aspirates of dogs. Am J Vet Res. 2003 May;64(5):544-9.


The RT-PCR assay was performed by use of tyrosinase, Melan-A, gp100, tyrosinase-related protein 2 (TRP-2), or melanoma antigen-encoding gene B (MAGE-B)-specific primers.
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11449353 Benlalam H, Labarriere N, Linard B, Derre L, Diez E, Pandolfino MC, Bonneville M, Jotereau F: Comprehensive analysis of the frequency of recognition of melanoma-associated antigen (MAA) by CD8 melanoma infiltrating lymphocytes (TIL): implications for immunotherapy. Eur J Immunol. 2001 Jul;31(7):2007-15.


Twenty-three (39%) TIL lines reacted to at least one melanoma antigen.
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9524710 Kim CJ, Cormier J, Roden M, Gritz L, Mazzara GP, Fetsch P, Hijazi Y, Lee KH, Rosenberg SA, Marincola FM: Use of recombinant poxviruses to stimulate anti-melanoma T cell reactivity. Ann Surg Oncol. 1998 Jan-Feb;5(1):64-76.


RESULTS: DC were infected with recombinant poxviruses and demonstrated specific melanoma antigen expression by immunohistochemistry, immunofluorescence, and intracellular FACS analysis.
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