| Name | CD4 |
|---|---|
| Synonyms | CD4; CD4 antigen (p55); CD4 molecule; CD4mut; T cell antigen T4/LEU3; T cell surface glycoprotein CD4; T cell surface antigen T4/Leu 3; T cell surface glycoprotein CD4 precursor… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19884905 | Matta B, Jha P, Bora PS, Bora NS: Antigen-specific tolerance inhibits autoimmune uveitis in pre-sensitized animals by deletion and CD4+CD25+ T-regulatory cells. Immunol Cell Biol. 2010 Feb;88(2):187-96. Epub 2009 Nov 3. The number of cells (total T cells, CD4 (+) T cells and CD8 (+) T cells) undergoing apoptosis dramatically increased in the popliteal lymph nodes (LNs) of the tolerized animals compared with non-tolerized animals. |
3(0,0,0,3) | Details |
| 19479064 | Olsen I, Tollefsen S, Aagaard C, Reitan LJ, Bannantine JP, Andersen P, Sollid LM, Lundin KE: Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients. Int J Cancer. 1991 Dec 2;49(6):823-30. |
2(0,0,0,2) | Details |
| 9331282 | Bora NS, Woon MD, Tandhasetti MT, Cirrito TP, Kaplan HJ: Induction of experimental autoimmune anterior uveitis by a self-antigen: complex without adjuvant. J Immunother. 2007 Jan;30(1):75-82. Adoptive transfer of CD4+ and CD8+ T cells was performed to investigate the pathogenesis of EAAU. |
2(0,0,0,2) | Details |
| 16455987 | Peng L, Ko E, Luo W, Wang X, Shrikant PA, Ferrone S: CD4-dependent potentiation of a high molecular weight-melanoma-associated antigen-specific CTL response elicited in HLA-A2/Kb transgenic mice. J Immunol. 2006 Feb 15;176(4):2307-15. |
3(0,0,0,3) | Details |
| 19134253 | Qiao XH, Xie XT, Jiang SY, Shi W, Li W, Zhou JJ: [Natural history of moderate aplastic anemia in children and effects of immunosuppressive therapy]. Zhonghua Er Ke Za Zhi. 2008 Dec;46(12):909-13. The level of CD4 (+), NK cell ratio decreased but the level of CD8 (+) cell increased in MAA children before the treatment. |
2(0,0,0,2) | Details |
| 18829565 | Maciag PC, Seavey MM, Pan ZK, Ferrone S, Paterson Y: Cancer immunotherapy targeting the high molecular weight melanoma-associated antigen protein results in a broad antitumor response and reduction of pericytes in the tumor vasculature. Cancer Res. 2008 Oct 1;68(19):8066-75. Immunization with Lm-LLO-HMW-MAA-C was able to impede the tumor growth of early established B16F10-HMW-MAA tumors in mice and both CD4 (+) and CD8 (+) T cells were required for therapeutic efficacy. |
1(0,0,0,1) | Details |
| 19357529 | Dejesus E, Young B, Morales-Ramirez JO, Sloan L, Ward DJ, Flaherty JF, Ebrahimi R, Maa JF, Reilly K, Ecker J, McColl D, Seekins D, Farajallah A: Simplification of antiretroviral therapy to a single-tablet regimen consisting of efavirenz, emtricitabine, and tenofovir disoproxil fumarate versus unmodified antiretroviral therapy in virologically suppressed HIV-1-infected patients. J Acquir Immune Defic Syndr. 2009 Jun 1;51(2):163-74. The arms were well balanced at baseline with 88% males, 29% blacks, and a mean age of 43 years; CD4 was 540 cells per cubic millimeter, 96% had HIV-1 RNA <50 copies per milliliter, and 88% were on their first ART regimen. |
1(0,0,0,1) | Details |
| 17962461 | Jha P, Matta B, Lyzogubov V, Tytarenko R, Bora PS, Bora NS: Crucial role of apoptosis in the resolution of experimental autoimmune anterior uveitis. Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5091-100. RESULTS: Flow cytometry, TUNEL staining, and light microscopy demonstrated that CD11b/c (+) and CD4 (+) T cells undergo apoptosis during EAAU. |
1(0,0,0,1) | Details |
| 7974496 | Holladay SD, Comment CE, Kwon J, Luster MI: Fetal hematopoietic alterations after maternal exposure to ethylene glycol monomethyl ether: prolymphoid cell targeting. Toxicol Appl Pharmacol. 1994 Nov;129(1):53-60. Flow cytometric analysis indicated that EGME treatment resulted in decreased percentages of CD4+8+ thymocytes and increased percentages of CD4-8- thymocytes. |
1(0,0,0,1) | Details |
| 9456433 | Cormier JN, Abati A, Fetsch P, Hijazi YM, Rosenberg SA, Marincola FM, Topalian SL: Comparative analysis of the in vivo expression of tyrosinase, MART-1/Melan-A, and gp100 in metastatic melanoma lesions: implications for immunotherapy. J Immunother. 1998 Jan;21(1):27-31. These Ag can be recognized by CD8+ and, in the case of tyrosinase, CD4+ T cells. |
1(0,0,0,1) | Details |
| 11779404 | Metharom P, Ellem KA, Schmidt C, Wei MQ: Lentiviral vector-mediated tyrosinase-related protein 2 gene transfer to dendritic cells for the therapy of melanoma. Hum Gene Ther. 2001 Dec 10;12(18):2203-13. Administration of mTRP-2 gene-modified DCs (DC-HR' CmT2) to C57BL/6 mice evoked strong protection against tumor challenge, for which the presence of CD4+ and CD8+ cells during both the priming and challenge phase was essential. |
1(0,0,0,1) | Details |
| 10073678 | Alvarez G, Lascurain R, Perez A, Degand P, Montano LF, Martinez-Cairo S, Zenteno E: Relevance of sialoglycoconjugates in murine thymocytes during maturation and selection in the thymus. Immunol Invest. 1999 Jan;28(1):9-18. The immature CD4-CD8- and CD4+CD8+ cortical thymocytes were recognized by SNA, whereas the mature single positive (CD4+ or CD8+) medullary cells, preferentially bound MAA lectin. |
1(0,0,0,1) | Details |
| 18928602 | Chen C, Wei J, Li YF, Huang SL, Fang JP, Zhou DH, Xue HM, Huang K: [Analysis of lymphocyte immune abnormality in 52 cases of children idiopathic aplastic anemia]. J Immunother Emphasis Tumor Immunol. 1994 Jul;16(1):24-35. The phenotypes of lymphocytes, the ratios of Th1/Th2 and Tc1/Tc2, the levels of CD25 (+) and CD4 (+) CD25 (+) T lymphocytes in peripheral blood of IAA patients were measured at the onset of disease by flow cytometry and were compared with that in normal controls. |
1(0,0,0,1) | Details |
| 14502218 | Okada N, Masunaga Y, Okada Y, Mizuguchi H, Iiyama S, Mori N, Sasaki A, Nakagawa S, Mayumi T, Hayakawa T, Fujita T, Yamamoto A: Dendritic cells transduced with gp100 gene by RGD fiber-mutant adenovirus vectors are highly efficacious in generating anti-B16BL6 melanoma immunity in mice. Gene Ther. 2003 Oct;10(22):1891-902. Furthermore, in vivo depletion analysis demonstrated that CD8 (+) CTLs and NK cells were the predominant effector cells responsible for the anti-B16BL6 immunity induced by vaccination with AdRGD-gp100/mBM-DCs, and that helper function of CD4 (+) T cells was necessary for sufficiently eliciting effector activity. These findings clearly revealed that highly efficient MAA gene transduction to DCs by AdRGD could greatly improve the efficacy of DC-based immunotherapy against melanoma. |
1(0,0,0,1) | Details |
| 14649623 | McComsey G, Maa JF: Host factors may be more important than choice of antiretrovirals in the development of lipoatrophy. AIDS Read. 2003 Nov;13(11):539-42 CD4 cell count and plasma tumor necrosis factor (TNF), soluble TNF receptors, and leptin levels were assessed and correlated with the development of lipoatrophy. |
1(0,0,0,1) | Details |
| 17198085 | Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ: Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. PLoS One. 2009 May 22;4(5):e5641. |
7(0,0,0,7) | Details |
| 1835714 | Radrizzani M, Benedetti B, Castelli C, Longo A, Ferrara GB, Herlyn M, Parmiani G, Fossati G: Human allogeneic melanoma-reactive T-helper lymphocyte clones: functional analysis of lymphocyte-melanoma interactions. 559. Lymphocyte clones were isolated from CD4+ peripheral-blood lymphocytes (PBL) of melanoma (Me) patient 9923 (HLA-DR7, DQw2, w6), co-cultured for 30 days with autologous accessory cells, allogeneic Me (Me 1811) (HLA-DR7, DQw1, w2), IL-1 beta (2 U/ml) and IL-2 (15 IU/ml). |
4(0,0,0,4) | Details |
| 8529406 | Kim MC, Kabeer NH, Tandhasetti MT, Kaplan HJ, Bora NS: Immunohistochemical studies on associated antigen (MAA) induced experimental autoimmune anterior uveitis (EAAU). Curr Eye Res. 1995 Aug;14(8):703-10. Immunohistology of the enucleated eyes was performed with monoclonal antibodies W3/25 (CD4), OX-8 (CD8), ED2 (macrophage), OX-33 (B cell), OX-6 (Ia), IA29 (ICAM-1) and WT.1 (LFA-1). |
3(0,0,0,3) | Details |