Protein Information

Name MAA2
Synonyms ANOP 2; ANOP2; BCL 6 corepressor; BCL6 co repressor; BCL6 corepressor; BCOR; BCoR protein; MAA 2…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
15004558 Ng D, Thakker N, Corcoran CM, Donnai D, Perveen R, Schneider A, Hadley DW, Tifft C, Zhang L, Wilkie AO, van der Smagt JJ, Gorlin RJ, Burgess SM, Bardwell VJ, Black GC, Biesecker LG: Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR. Nat Genet. 2004 Apr;36(4):411-6. Epub 2004 Mar 7.

7(0,0,0,7) Details
15770227 Horn D, Chyrek M, Kleier S, Luttgen S, Bolz H, Hinkel GK, Korenke GC, Riess A, Schell-Apacik C, Tinschert S, Wieczorek D, Gillessen-Kaesbach G, Kutsche K: Novel mutations in BCOR in three patients with oculo-facio-cardio-dental syndrome, but none in Lenz microphthalmia syndrome. Eur J Hum Genet. 2005 May;13(5):563-9.

4(0,0,0,4) Details
17961210 Nicholls JM, Bourne AJ, Chen H, Guan Y, Peiris JS: Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses. Respir Res. 2007 Oct 25;8:73.


In addition we found that there were differences in tissue distribution of the alpha2,3 linked SA when 2 different isoforms of MAA (MAA1 and MAA2) lectin were used.
3(0,0,0,3) Details
20209520 Kapoerchan VV, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Ferraces-Casais P, Llamas-Saiz AL, van Raaij MJ, van Doorn J, van der Marel GA, Overkleeft HS, Overhand M: Gramicidin S Derivatives Containing cis- and trans-Morpholine Amino Acids (MAAs) as Turn Mimetics. Chemistry. 2010 Mar 5;16(14):4259-4265.

For this purpose, one of the D-Phe-Pro two-residue turn motifs in the rigid cyclic beta-hairpin structure of GS was replaced with morpholine amino acids (MAA 2-5), differing in stereochemistry and length of the side-chain.
We show that compound 8, containing the dipeptide isostere trans-MAA 4, has an apparent high structural resemblance with GS and that its antibacterial activity against a panel of Gram positive and -negative bacterial strains is better than the derivatives 6, 7 and 9.
1(0,0,0,1) Details