Protein Information

Name transferase
Synonyms 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
8699407 Jones CJ, Kimber SJ, Illingworth I, Aplin JD: Decidual sialylation shows species-specific differences in the pregnant mouse and rat. J Reprod Fertil. 1996 Mar;106(2):241-50.


However, the species-specific expression of alpha 2,3-linked sialyl residues suggests distinct patterns of steroidally modulated sialyl transferase expression.
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9876022 Krishnamurthy H, Weinbauer GF, Aslam H, Yeung CH, Nieschlag E: Quantification of apoptotic testicular germ cells in normal and methoxyacetic acid-treated mice as determined by flow cytometry. J Androl. 1998 Nov-Dec;19(6):710-7.


DNA strand breaks generated by the activation of endogenous endonuclease in the apoptotic germ cells were detected by the in situ labeling of the 3'-OH termini with biotinylated dUTP in the presence of terminal deoxynucleotidyl transferase (TUNEL technique).
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7678157 Ma H, An J, Hsie AW, Au WW: Mutagenicity and cytotoxicity of 2-methoxyethanol and its metabolites in Chinese hamster cells (the CHO/HPRT and AS52/GPT assays). Mutat Res. 1993 Jan;298(3):219-25.


We have determined the mutagenicity of these compounds at the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus in CHO-K1-BH4 cells (CHO/HPRT assay) and the xanthine-guanine phosphoribosyl transferase (gpt) locus in CHO AS52 cells (AS52/GPT assay).
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1628807 Dutcher SK, Galloway RE, Barclay WR, Poortinga G: Tryptophan analog resistance mutations in Chlamydomonas reinhardtii. Genetics. 1992 Jul;131(3):593-607.


These include the combined activities of anthranilate phosphoribosyl transferase, phosphoribosyl anthranilate isomerase, indoleglycerol phosphate synthetase and anthranilate synthase.
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18785521 Hou G, Wang QY, Wang XQ, Kang J, Yu RJ: [Effects of vitamin A on the proliferation and apoptosis of alveolar cells of experimental emphysema in rats]. Zhonghua Jie He He Hu Xi Za Zhi. 2008 Mar;31(3):209-12.


The apoptosis of the alveolar cells was observed by the method of terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL).
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17822625 Chen LD, Liu J, Yu XF, Pang DW, Wang QQ, Yuan HY, Tang ZY, Li Y: [In-vivo targeted imaging of hepatocellular carcinoma in nude mice using quantum dot probes]. Zhonghua Bing Li Xue Za Zhi. 2007 Jun;36(6):394-9.


Serum levels of alanine amino transferase, aspartate amino transferase, blood urea nitrogen and creatinine were determined by conventional biochemical analysis.
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16179866 Kamei T, Inui M, Nakase M, Nakamura S, Okumura K, Hiramoto K, Tagawa T: Experimental therapy using interferon-gamma and anti-Fas antibody against oral malignant melanoma cells. Melanoma Res. 2005 Oct;15(5):393-400.


In the histological study, the combined administration group tested positive in terminal deoxynucleotidyl transferase-mediated nick end labelling staining, and showed significantly increased levels of Fas expression on immunostaining compared with the vehicle group.
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7758252 Levy M, Zylber-Katz E, Rosenkranz B: Clinical pharmacokinetics of dipyrone and its metabolites. . Clin Pharmacokinet. 1995 Mar;28(3):216-34.


MAA is further metabolised with a mean elimination half-life (t1/2) of 2.6 to 3.5 hours to 4-formyl-amino-antipyrine (FAA), which is an end-metabolite, and to 4-amino-antipyrine (AA), which is then acetylated to 4-acetyl-amino-antipyrine (AAA) by the polymorphic N-acetyl-transferase (t1/2 of AA is 3.8 hours in rapid acetylators and 5.5 hours in slow acetylators).
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10969735 Kido T, Namiki H: Expression of testicular fatty acid-binding protein PERF 15 during germ cell apoptosis. Dev Growth Differ. 2000 Aug;42(4):359-66.


To determine whether PERF 15 participates in germ cell apoptosis, juvenile rat testis was examined by immunohistochemical and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) methods.
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