Name | caspase (protein family or complex) |
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Synonyms | caspase; caspases |
Name | MAA |
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CAS | methylarsonic acid |
PubMed | Abstract | RScore(About this table) | |
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12504796 | Garcia-Martinez JM, Fresno Vara JA, Lastres P, Bernabeu C, Betes PO, Martin-Perez J: Effect of metamizol on promyelocytic and terminally differentiated granulocytic cells. Biochem Pharmacol. 2003 Jan 15;65(2):209-17. Again, the HL60 promyelocytes were more sensitive to apoptosis than granulocytic differentiated cells, as measured by the percentage of sub-G (1) cells detected by flow cytometry and by determination of caspase activity as a function of poly (ADP- polymerase cleavage. |
1(0,0,0,1) | Details |
18179559 | Bagchi G, Waxman DJ: Toxicity of ethylene glycol monomethyl ether: impact on testicular gene expression. Int J Androl. 2008 Apr;31(2):269-74. Epub 2007 Dec 30. Oxidative stress in spermatocytes exposed to MAA triggers mitochondrial release of cytochrome C, activation of caspases and ultimately apoptosis. |
1(0,0,0,1) | Details |
15182728 | Willis MS, Klassen LW, Carlson DL, Brouse CF, Thiele GM: Malondialdehyde-binds macrophage scavenger receptor (s) and induces lysosomal damage. Int Immunopharmacol. 2004 Jul;4(7):885-99. Moreover, MAA-haptenated proteins are demonstrated to be associated with a rapid dose-dependent disruption in lysosomal integrity, resulting in leakage and caspase activation. |
haptenated protein 1(0,0,0,1) | Details |
16179866 | Kamei T, Inui M, Nakase M, Nakamura S, Okumura K, Hiramoto K, Tagawa T: Experimental therapy using interferon-gamma and anti-Fas antibody against oral malignant melanoma cells. Melanoma Res. 2005 Oct;15(5):393-400. Moreover, inhibition of IFN-gamma/CH-11-induced apoptosis with a general caspase inhibitor (benzyloxycarbonyl-Val- -Asp-fluoromethylketone) reduced cell death significantly in vitro. |
1(0,0,0,1) | Details |