Protein Information

Name c Src
Synonyms ASV; SRC1; Avian sarcoma virus protein; Proto oncogene tyrosine protein kinase SRC; SRC; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC 1; c SRC…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
10075741 Biscardi JS, Maa MC, Tice DA, Cox ME, Leu TH, Parsons SJ: c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J Biol Chem. 1999 Mar 19;274(12):8335-43.

8(0,0,0,8) Details
1281304 Maa MC, Wilson LK, Moyers JS, Vines RR, Parsons JT, Parsons SJ: Identification and characterization of a cytoskeleton-associated, epidermal growth factor sensitive pp60c-src substrate. Oncogene. 1992 Dec;7(12):2429-38.

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7542783 Maa MC, Leu TH, McCarley DJ, Schatzman RC, Parsons SJ: Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6981-5.

7(0,0,0,7) Details
16001424 Lee JC, Maa MC, Yu HS, Wang JH, Yen CK, Wang ST, Chen YJ, Liu Y, Jin YT, Leu TH: Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells. Mol Carcinog. 2005 Aug;43(4):207-14.

6(0,0,0,6) Details
12456372 Leu TH, Maa MC: Functional implication of the interaction between EGF receptor and c-Src. . Front Biosci. 2003 Jan 1;8:s28-38.

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15869794 Leu TH, Charoenfuprasert S, Yen CK, Fan CW, Maa MC: Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages. Mol Immunol. 2006 Feb;43(4):308-16.

4(0,0,0,4) Details
10698670 Wang W, Wine RN, Chapin RE: Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis. Toxicol Appl Pharmacol. 2000 Mar 1;163(2):125-34.


We evaluated the role of tyrosine kinase pp60 (c-src) in control and EGME-treated adult rat testis in vivo, as well as in vitro using cultured adult rat seminiferous tubules treated with MAA.
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