| Name | melan A |
|---|---|
| Synonyms | Antigen LB39 AA; Antigen SK29 AA; MART 1; MART1; MLANA; Melan A; Melan A protein; Melanoma antigen recognized by T cells 1… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8811494 | Marincola FM, Hijazi YM, Fetsch P, Salgaller ML, Rivoltini L, Cormier J, Simonis TB, Duray PH, Herlyn M, Kawakami Y, Rosenberg SA: Analysis of expression of the melanoma-associated antigens MART-1 and gp100 in metastatic melanoma cell lines and in in situ lesions. J Immunother Emphasis Tumor Immunol. 1996 May;19(3):192-205. |
7(0,0,0,7) | Details |
| 18519770 | Goto Y, Ferrone S, Arigami T, Kitago M, Tanemura A, Sunami E, Nguyen SL, Turner RR, Morton DL, Hoon DS: Human high molecular weight-melanoma-associated antigen: utility for detection of metastatic melanoma in sentinel lymph nodes. Clin Cancer Res. 2008 Jun 1;14(11):3401-7. Immunohistochemical staining (IHC) using S-100p-HMB-45-, and MART-1-specific antibodies is used for detecting metastases in sentinel lymph nodes (SLN). |
6(0,0,0,6) | Details |
| 15305155 | Murer K, Urosevic M, Willers J, Selvam P, Laine E, Burg G, Dummer R: Expression of Melan-A/MART-1 in primary melanoma cell cultures has prognostic implication in metastatic melanoma patients. Melanoma Res. 2004 Aug;14(4):257-62. |
5(0,0,0,5) | Details |
| 9220317 | Kim CJ, Prevette T, Cormier J, Overwijk W, Roden M, Restifo NP, Rosenberg SA, Marincola FM: Dendritic cells infected with poxviruses encoding MART-1/Melan A sensitize T lymphocytes in vitro. J Immunother. 1997 Jul;20(4):276-86. |
4(0,0,0,4) | Details |
| 9456433 | Cormier JN, Abati A, Fetsch P, Hijazi YM, Rosenberg SA, Marincola FM, Topalian SL: Comparative analysis of the in vivo expression of tyrosinase, MART-1/Melan-A, and gp100 in metastatic melanoma lesions: implications for immunotherapy. J Immunother. 1998 Jan;21(1):27-31. |
4(0,0,0,4) | Details |
| 15623750 | van Dinten LC, Pul N, van Nieuwpoort AF, Out CJ, Jager MJ, van den Elsen PJ: Uveal and cutaneous melanoma: shared expression characteristics of melanoma-associated antigens. Invest Ophthalmol Vis Sci. 2005 Jan;46(1):24-30. METHODS: The expression of the MAA Melan-A/MART-1 was analyzed in 10 uveal and 10 cutaneous patient-derived melanoma cell lines by Western blot analysis and RT-PCR. |
4(0,0,0,4) | Details |
| 12755292 | Catchpole B, Gould SM, Kellett-Gregory LM, Dobson JM: Development of a multiple-marker polymerase chain reaction assay for detection of metastatic melanoma in lymph node aspirates of dogs. Am J Vet Res. 2003 May;64(5):544-9. The RT-PCR assay was performed by use of tyrosinase, Melan-A, gp100, tyrosinase-related protein 2 (TRP-2), or melanoma antigen-encoding gene B (MAGE-B)-specific primers. |
3(0,0,0,3) | Details |
| 9466650 | Cormier JN, Hijazi YM, Abati A, Fetsch P, Bettinotti M, Steinberg SM, Rosenberg SA, Marincola FM: Heterogeneous expression of melanoma-associated antigens and HLA-A2 in metastatic melanoma in vivo. Int J Cancer. 1998 Feb 9;75(4):517-24. MART-1/MelanA and Pmel17/gp100 are melanoma-associated antigens (MAAs) that can be recognized by tumor-infiltrating lymphocytes (TILs) capable of mediating successful adoptive therapy in vivo. |
3(0,0,0,3) | Details |
| 15946236 | Urosevic M, Braun B, Willers J, Burg G, Dummer R: Expression of melanoma-associated antigens in melanoma cell cultures. Exp Dermatol. 2005 Jul;14(7):491-7. We investigated the expression of five MAA - Melan-A/MART-1, tyrosinase, gp100, MAGE-1 and MAGE-3 - by means of FACS analysis in 50 melanoma cell cultures and compared them to the cultures of human foreskin-derived melanocytes and melanoma cell line UKRV-Mel2. |
3(0,0,0,3) | Details |
| 9579583 | Li M, Xu F, Muller J, Hearing VJ, Gorelik E: Ecotropic C-type retrovirus of B16 melanoma and malignant transformation of normal melanocytes. Int J Cancer. 1998 May 4;76(3):430-6. To test this, normal melanocyte lines (melan-a and C57M) of C57BL/6 mice were infected with the MelARV produced by B16BL6 melanoma. |
2(0,0,0,2) | Details |
| 19951123 | Stell AJ, Dobson JM, Scase TJ, Catchpole B: Evaluation of variants of melanoma-associated antigen genes and mRNA transcripts in melanomas of dogs. Am J Vet Res. 2009 Dec;70(12):1512-20. A PCR assay was performed by use of Melan-A, SILV, or tyrosinase-specific primers. |
2(0,0,0,2) | Details |
| 19233913 | Kitago M, Koyanagi K, Nakamura T, Goto Y, Faries M, O'Day SJ, Morton DL, Ferrone S, Hoon DS: mRNA expression and BRAF mutation in circulating melanoma cells isolated from peripheral blood with high molecular weight melanoma-associated antigen-specific monoclonal antibody beads. Clin Chem. 2009 Apr;55(4):757-64. Epub 2009 Feb 20. Testing for the expression of a melanoma-associated gene panel (MLANA, MAGEA3, and MITF) with qRT-PCR and for the presence of BRAFmt (a BRAF gene variant encoding the V600E mutant protein) verified the beads-isolated CTCs to be melanoma cells. |
2(0,0,0,2) | Details |
| 9524710 | Kim CJ, Cormier J, Roden M, Gritz L, Mazzara GP, Fetsch P, Hijazi Y, Lee KH, Rosenberg SA, Marincola FM: Use of recombinant poxviruses to stimulate anti-melanoma T cell reactivity. Ann Surg Oncol. 1998 Jan-Feb;5(1):64-76. The efficiency of infection and expression of the MART-1 antigen were assessed by immunohistochemistry and intracellular FACS analyses. |
2(0,0,0,2) | Details |
| 10737389 | Ogg GS, Dunbar PR, Cerundolo V, McMichael AJ, Lemoine NR, Savage P: Sensitization of tumour cells to lysis by virus-specific CTL using antibody-targeted MHC class I/peptide complexes. Br J Cancer. 2000 Mar;82(5):1058-62. CTL specific for HLA-A2/gag efficiently lysed complex-targeted cells, while control CTL (specific for an HLA-A2.1-restricted epitope of melan-A) did not. |
1(0,0,0,1) | Details |
| 12543800 | Takeuchi H, Kuo C, Morton DL, Wang HJ, Hoon DS: Expression of differentiation melanoma-associated antigen genes is associated with favorable disease outcome in advanced-stage melanomas. Cancer Res. 2003 Jan 15;63(2):441-8. We focused on three known differentiation MAAs: tyrosinase (TYR), TYR-related protein 2 (TRP-2), and melanoma antigen recognized by T cells 1 (MART-1); all three of them are known to induce immune responses in melanoma patients and are frequently expressed in melanomas. |
1(0,0,0,1) | Details |
| 10653598 | Castelli C, Rivoltini L, Andreola G, Carrabba M, Renkvist N, Parmiani G: T-cell recognition of melanoma-associated antigens. . J Cell Physiol. 2000 Mar;182(3):323-31. These antigens belong to three main groups: tumor-associated testis-specific antigens (e.g. , MAGE, BAGE, and GAGE); melanocyte differentiation antigens (e.g., tyrosinase, Melan-A/MART-1); and mutated or aberrantly expressed molecules (e.g, CDK4, MUM-1, beta-catenin). |
1(0,0,0,1) | Details |
| 18652234 | Moiseenko VM, Danilova AB, Danilov AO, Turkevich EA, Baldueva IA, Matsko DE: [An immunocytochemical investigation of antigen expression by skin melanoma cells cultured for vaccine production]. Vopr Onkol. 2008;54(3):303-14. As of now, several varieties of melanoma-associated antigens (MAA) have been identified: MART1/melan A, tyrosinase, MITF, gp100, members of MAGE family, S100, CD63 and CD146. |
1(0,0,0,1) | Details |
| 9102226 | Sarantou T, Chi DD, Garrison DA, Conrad AJ, Schmid P, Morton DL, Hoon DS: Melanoma-associated antigens as messenger RNA detection markers for melanoma. Cancer Res. 1997 Apr 1;57(7):1371-6. Melanoma cell lines, melanocytes (cultured), primary and metastatic malignant melanoma tissues, and blood from patients with American Joint Committee on Cancer stage I-IV melanoma were assessed for tyrosinase, tyrosinase-related proteins 1 and 2, Pmel 17, and MART-1/Melan-A. |
1(0,0,0,1) | Details |
| 9810766 | Zeuthen J, Dzhandzhugazyan K, Hansen MR, Kirkin AF: The immunogenic properties of human melanomas and melanoma-associated antigens recognized by cytotoxic T lymphocytes. Bratisl Lek Listy. 1998 Aug-Sep;99(8-9):426-34. These antigens belong to three main groups: tumor-associated testis-specific antigens (MAGE, BAGE, GAGE and PRAME), melanocyte differentiation antigens (tyrosinase, Melan-A/MART-1, gp100, TRP-1 and TRP-2) and mutated or aberrantly expressed antigens (MUM-1, CDK4, beta-catenin, gp100-in4, p15 and N-acetylglucosaminyltransferase V). |
1(0,0,0,1) | Details |
| 11449353 | Benlalam H, Labarriere N, Linard B, Derre L, Diez E, Pandolfino MC, Bonneville M, Jotereau F: Comprehensive analysis of the frequency of recognition of melanoma-associated antigen (MAA) by CD8 melanoma infiltrating lymphocytes (TIL): implications for immunotherapy. Eur J Immunol. 2001 Jul;31(7):2007-15. Melanosomal proteins were recognized by 19 TIL populations and the most prominent responses against these proteins were directed against Melan-A/MART-1 (mainly in association with HLA-A*0201) and gp100 (in association with diverse HLA contexts). |
1(0,0,0,1) | Details |