Name | interferon gamma |
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Synonyms | IFG; IFI; IFN gamma; IFNG; IFNgamma; Immune interferon; Interferon gamma; Interferon gamma precursor… |
Name | MAA |
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CAS | methylarsonic acid |
PubMed | Abstract | RScore(About this table) | |
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12690298 | Kamei T, Inui M, Nakamura S, Okumura K, Goto A, Tagawa T: Interferon-gamma and anti-Fas antibody-induced apoptosis in human melanoma cell lines and its relationship to bcl-2 cleavage and bak expression. Melanoma Res. 2003 Apr;13(2):153-9. |
8(0,0,0,8) | Details |
15577316 | Kovalcsik E, John J, Turner M, Birchall L, Sage D, Whittle R, Dalgleish A, Pandha H: Differential expression of melanoma-associated antigens and molecules involved in antigen processing and presentation in three cell lines established from a single patient. Melanoma Res. 2004 Dec;14(6):463-71. Interferon-gamma (IFNgamma) treatment increased the expression of HLA class I and transporters associated with antigen processing 1 (TAP1) in all three cell lines. |
4(0,0,0,4) | Details |
3079589 | Taramelli D, Fossati G, Mazzocchi A, Delia D, Ferrone S, Parmiani G: Classes I and II HLA and melanoma-associated antigen expression and modulation on melanoma cells isolated from primary and metastatic lesions. Cancer Res. 1986 Jan;46(1):433-9. In vitro incubation with partially purified or recombinant human gamma-interferon enhanced the expression of HLA-DR antigens on all short-term cultured melanoma cells tested but induced and/or augmented the expression of HLA-DQ antigens only in 5 of the 8 cases examined. |
2(0,0,0,2) | Details |
3129542 | Murray JL, Stuckey SE, Pillow JK, Rosenblum MG, Gutterman JU: Differential in vitro effects of recombinant alpha-interferon and recombinant gamma-interferon alone or in combination on the expression of melanoma-associated surface antigens. J Biol Response Mod. 1988 Apr;7(2):152-61. |
2(0,0,0,2) | Details |
7496156 | Kim TS, Xu WS, Sun T, Cohen EP: Immunization with interleukin-2/interferon-gamma double cytokine-secreting allogeneic fibroblasts prolongs the survival of mice with melanoma. Melanoma Res. 1995 Aug;5(4):217-27. |
2(0,0,0,2) | Details |
11023194 | Fujii S, Huang S, Fong TC, Ando D, Burrows F, Jolly DJ, Nemunaitis J, Hoon DS: Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-gamma retroviral vector in melanoma patients. Cancer Gene Ther. 2000 Sep;7(9):1220-30. |
2(0,0,0,2) | Details |
3093392 | Anichini A, Mortarini R, Fossati G, Parmiani G: Phenotypic profile of clones from early cultures of human metastatic melanomas and its modulation by recombinant interferon gamma. Int J Cancer. 1986 Oct 15;38(4):505-11. |
2(0,0,0,2) | Details |
16179866 | Kamei T, Inui M, Nakase M, Nakamura S, Okumura K, Hiramoto K, Tagawa T: Experimental therapy using interferon-gamma and anti-Fas antibody against oral malignant melanoma cells. Melanoma Res. 2005 Oct;15(5):393-400. |
2(0,0,0,2) | Details |
9924695 | Coral S, Sigalotti L, Gasparollo A, Cattarossi I, Visintin A, Cattelan A, Altomonte M, Maio M: Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2'- (5-AZA-CdR). J Immunother. 1999 Jan;22(1):16-24. These observations, together with data obtained comparing the effect of 5-AZA-CdR with that of interferon-gamma, strongly suggest that 5-AZA-CdR may have prospective therapeutic implications in active and/or passive specific immunotherapy for human melanoma. |
1(0,0,0,1) | Details |
10561459 | Rapoport E, Pendu JL: Glycosylation alterations of cells in late phase apoptosis from colon carcinomas. Glycobiology. 1999 Dec;9(12):1337-45. This could be attributed to the IFNgamma preteatment required to induce Fas expression on these cells. |
1(0,0,0,1) | Details |
18832572 | Matta B, Jha P, Bora PS, Bora NS: Tolerance to uveitis is mediated by CD4+CD25+ T-regulatory cells. Am J Pathol. 2008 Nov;173(5):1440-54. Epub 2008 Oct 2. Expression levels of both interleukin-10 and transforming growth factor-beta2 were elevated whereas reduced levels of tumor necrosis factor-alpha, interferon-gamma, and interleukin-2 were detected in tolerance-induced animals. |
-associated antigen in autoimmune 1(0,0,0,1) | Details |
12806279 | Nolte A, Scheffold C, Slotty J, Huenefeld C, Schultze JL, Grabbe S, Berdel WE, Kienast J: Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy. J Immunother. 2003 May-Jun;26(3):257-69. Specific cytolytic activity was accompanied by interferon-gamma secretion. |
1(0,0,0,1) | Details |
19884905 | Matta B, Jha P, Bora PS, Bora NS: Antigen-specific tolerance inhibits autoimmune uveitis in pre-sensitized animals by deletion and CD4+CD25+ T-regulatory cells. Immunol Cell Biol. 2010 Feb;88(2):187-96. Epub 2009 Nov 3. The level of interferon (IFN)-gamma and IL-2 decreased, whereas TGF-beta2 was elevated in the state of tolerance. |
1(0,0,0,1) | Details |
3622556 | Cerny T, Owens SE, Mackenzie SA, Nuttall PM, Gosh AK, Smith DB, Thatcher N: Immunoscintigraphy with 99mTc labelled F (ab') 2 fragments of an anti melanoma monoclonal antibody (225.28S) in patients with metastatic malignant melanoma. Eur J Nucl Med. 1987;13(3):130-3. In four cases, imaging was repeated following treatment with recombinant gamma interferon. |
1(0,0,0,1) | Details |
1643429 | Vlock DR, Toporowicz A, Arnold B: Modulation by interferon alpha and gamma of the expression of a melanoma-associated antigen detected by autologous antibody. Melanoma Res. 1992 Jul;2(2):105-14. Nine melanoma cell lines were incubated for 3 days with 0.01-100 units/ml of interferon alpha (IFN-alpha) or interferon gamma (IFN-gamma) and the maximum titre of autologous antibody reactivity was determined by protein A haemadsorption. |
1(0,0,0,1) | Details |
18713811 | Lim SF, Lee MM, Zhang P, Song Z: The Golgi CMP-transporter: A new CHO mutant provides functional insights. Glycobiology. 2008 Nov;18(11):851-60. Epub 2008 Aug 19. Biochemical analyses indicate that recombinant interferon-gamma (IFN-gamma) produced by the mutant cells lack |
1(0,0,0,1) | Details |
3888384 | Parmiani G, Fossati G, Taramelli D, Anichini A, Balsari A, Gambacorti-Passerini C, Sciorelli G, Cascinelli N: Autologous cellular immune response to primary and metastatic human melanomas and its regulation by DR antigens expressed on tumor cells. Cancer Metastasis Rev. 1985;4(1):7-26. The modulation of DR antigens on Me cells by Interferon-gamma correlated positively with their suppressive capacity. |
1(0,0,0,1) | Details |
2944474 | Fisher PB, Hermo H Jr, Solowey WE, Dietrich MC, Edwalds GM, Weinstein IB, Langer JA, Pestka S, Giacomini P, Kusama M, et al.: Effect of recombinant human fibroblast interferon and mezerein on growth, differentiation, immune interferon binding and tumor associated antigen expression in human melanoma cells. Anticancer Res. 1986 Jul-Aug;6(4):765-74. In the present study we have further analyzed this synergistic interaction and have also evaluated the effect of IFN-delta and MEZ, alone and in combination, on recombinant human gamma interferon (IFN-gamma) binding and Class I HLA and melanoma associated antigen (MAA) expression in the HO-1 human melanoma cell line. |
1(0,0,0,1) | Details |