| Name | c erb B2 |
|---|---|
| Synonyms | C erb B2; NEU; C erb B2/neu protein; C erbB 2; CD340 antigen; ERBB 2; ERBB2; ErbB 2 isoform a… |
| Name | MAMA |
|---|---|
| CAS | ammonium hydrogen methylarsonate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10945166 | Schneider J, Lucas R, Sanchez J, Tejerina A, Ruibal A: Cellular accumulation of uPA-PAI-1 [correction of UPA-PAI-1] and uPA-PAI-2 [correction of UPA-PAI-2] complexes in early (pT1) breast cancer: a new link in the uPA-UPAr-PAI chain. In Vivo. 2000 Jul-Aug;14(4):507-11. In addition, CD44std, Ki67, c-erb-B2, p53, ER and PR expression were studied on the same tissue samples by the same method. |
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| 11205274 | Schneider J, Lucas R, Sanchez J, Ruibal A, Tejerina A, Martin M: Modulation of molecular marker expression by induction chemotherapy in locally advanced breast cancer: correlation with the response to therapy and the expression of MDR1 and LRP. Anticancer Res. 2000 Nov-Dec;20(6B):4373-7. METHODS: Between 1995 and 1999, 48 patients with locally advanced breast cancer were submitted to induction chemotherapy at Fundacion Tejerina--Centro de Patologia de la Mama, Madrid, Spain. Core biopsies were performed in all cases prior to treatment for histological diagnosis which allowed for the determination of the following parameters by means of immunohistochemistry: hormone receptors (ER and PR), oncogenes and tumor suppressor genes (c-erb-B2 and p53) and the proliferation marker Ki67. |
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| 10567878 | Schneider J, Pollan M, Ruibal A, Jimenez E, Lucas AR, Nunez MI, Sanchez J, Tejerina A: Histologic grade and CD44 are independent predictors of axillary lymph node invasion in early (T1) breast cancer. Tumour Biol. 1999 Nov-Dec;20(6):319-30. Patients and Methods: We reviewed the records of 135 patients with unifocal invasive breast cancers, 2 cm or less in diameter, operated upon at 'Fundacion Tejerina-Centro de Patologia de la Mama', Madrid, Spain, between January 1993 and December 1997. Additionally, Ki67, c-erb-B2, p53, nm23, HSP27, HSP60 and CD44std expression was studied on archival, paraffin-embedded tumor material from these same patients by means of immunohistochemistry. |
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| 15980994 | Martinez-Arribas F, Nunez-Villar MJ, Lucas AR, Sanchez J, Tejerina A, Schneider J: The S-phase fraction of the aneuploid cell subpopulation is the biologically relevant one in aneuploid breast cancers. Breast Cancer Res Treat. 2005 Jul;92(1):77-80. Flow cytometry was performed on fresh tumor tissue, and immunohistochemistry for hormone receptors, Ki67, c-erb-B2 and p53 on paraffin-embedded material. |
1(0,0,0,1) | Details |
| 16552754 | Martinez-Arribas F, Agudo D, Pollan M, Gomez-Esquer F, Diaz-Gil G, Lucas R, Schneider J: Positive correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer. J Cell Biochem. 2006 Apr 15;97(6):1275-82. Markers of hormone dependence and progesterone receptors), proliferation (Ki67 and DNA-ploidy), angiogenesis (VEGF and CD105), as well as oncogene (c-erb-B2), and tumor suppressor gene (p53) expression were also analyzed. |
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| 12680147 | Martinez-Arribas F, Nunez-Villar MJ, Lucas AR, Sanchez J, Tejerina A, Schneider J: Immunofluorometric study of Bcl-2 and Bax expression in clinical fresh tumor samples from breast cancer patients. Anticancer Res. 2003 Jan-Feb;23(1B):565-8. Paraffin blocks corresponding to the same tumors were used for immunohistochemistry, to study the expression of hormone receptors (ER and PR), p53, c-erb-B2 and the Ki67 labelling index. |
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| 18204202 | Schneider J, Tejerina A, Perea C, Lucas R, Sanchez J: Molecular subgroups of small (pT1) breast carcinomas belonging exclusively to the ductal infiltrating variety. Cancer Genomics Proteomics. 2007 Nov-Dec;4(6):399-402. MATERIALS AND METHODS: This study was restricted to the ductal infiltrating variety only, and to pT1 size using the immunohistochemical markers estrogen receptor (ER), progesterone receptor (PR), HER2 and cytokeratin 5/6. |
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| 17352236 | Martinez-Arribas F, Alvarez T, Del Val G, Martin-Garabato E, Nunez-Villar MJ, Lucas R, Sanchez J, Tejerina A, Schneider J: Bcl-2 expression in breast cancer: a comparative study at the mRNA and protein level. Anticancer Res. 2007 Jan-Feb;27(1A):219-22. Additionally, the expression of hormone receptors (ER and PR), c-erb-B2, p53 and the proliferation-associated Ki-67 antigen were also studied by means of immunohistochemistry as part of the standard pathological workup. |
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| 15816610 | Hernandez L, Nunez-Villarl MJ, Martinez-Arribas F, Pollan M, Schneider J: Circulating hormone levels in breast cancer patients. correlation with serum tumor markers and the clinical and biological features of the tumors. Anticancer Res. 2005 Jan-Feb;25(1B):451-4. All tumors were studied after surgery for hormone receptor (ER and PR), Ki67, c-erb-B2 and p53 expression by means of immunohistochemistry, and for DNA-ploidy by means of flow cytometry. |
3(0,0,0,3) | Details |
| 16475699 | Martinez-Arribas F, Martin-Garabato E, Lafuente P, Tejerina A, Lucas R, Sanchez J, Schneider J: Proliferation measurement in breast cancer by two different methods. Anticancer Res. 2006 Jan-Feb;26(1A):199-202. Furthermore, hormone receptor (estrogen receptor, ER; progesterone receptor, PR), c-erb-B2 and p53 expressions were studied using the same method. |
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| 19035283 | Martinez-Arribas F, Martin-Garabato E, Zapardiel I, Sanchez J, Lucas AR, Tejerina A, Schneider J: Bax expression in untreated breast cancer: an immunocytometric study of 255 cases. Anticancer Res. 2008 Sep-Oct;28(5A):2595-8. As variables of the study for the final statistical analysis, the histological variety of the tumors, histological and nuclear grade, the expression of hormone receptors, p53, Ki-67 or c-erb-B2, axillary node invasion, tumor size and DNA-ploidy were also included. |
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| 18820371 | Martin-Garabato E, Martinez-Arribas F, Pollan M, Lucas AR, Sanchez J, Schneider J: The small variant of the apoptosis-associated X-chromosome RBM10 gene is co-expressed with caspase-3 in breast cancer. Cancer Genomics Proteomics. 2008 May-Aug;5(3-4):169-73. The correlation with the expression of hormone receptors, c-erb-B2, mutant p53 and Ki-67, all measured by means of immunohistochemistry, was also studied, as well as that with standard clinical parameters such as histological type, tumor size, axillary metastasis and DNA-ploidy. |
1(0,0,0,1) | Details |
| 12556966 | Schneider J, Pollan M, Tejerina A, Sanchez J, Lucas AR: Accumulation of uPA-PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer. Br J Cancer. 2003 Jan 13;88(1):96-101. Using this technique, we have studied a series of 212 early (pT1) unifocal breast cancers and have correlated the expression of uPA-PAI-1 complexes, together with other clinical and biological features (histologic variety, histologic and nuclear grade, hormone receptors, Ki67 labelling index, c-erb-B2-, p53- and CD44std-expression) with or without the occurrence of axillary node invasion. |
1(0,0,0,1) | Details |
| 11305953 | Schneider J, Gonzalez-Roces S, Pollan M, Lucas R, Tejerina A, Martin M, Alba A: Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy. Breast Cancer Res. 2001;3(3):183-91. Epub 2001 Feb 1. Immunohistochemistry for detecting the expression of c-erb-B2, p53, Ki67, estrogen receptor and progesterone receptor are routinely performed in our laboratory in every case, and the results obtained were included in the study. |
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