Name | p38alpha |
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Synonyms | CSAID binding protein 1; Protein serine/threonine kinase; p38; CSAID binding protein 2; CSAID binding protein; CSBP; CSBP 1; CSBP 2… |
Name | sodium arsenite |
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CAS | sodium arsenenite |
PubMed | Abstract | RScore(About this table) | |
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12749847 | Fernando P, Megeney LA, Heikkila JJ: Phosphorylation-dependent structural alterations in the small hsp30 chaperone are associated with cellular recovery. Exp Cell Res. 2003 Jun 10;286(2):175-85. Both heat stress and sodium arsenite treatment in A6 cells resulted in a rapid activation of p38alpha and MAPKAPK-2. |
81(1,1,1,1) | Details |
10704466 | Allen M, Svensson L, Roach M, Hambor J, McNeish J, Gabel CA: Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells. J Exp Med. 2000 Mar 6;191(5):859-70. |
4(0,0,0,4) | Details |
17373649 | Li JP, Yang JL: Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite. J Cell Physiol. 2007 Aug;212(2):481-8. Under arsenite, inhibition of p38 activation or depletion of p38alpha suppressed cyclin B1 ubiquitination and proteolysis, while forced expression of MKK6-p38 accelerated these events. |
1(0,0,0,1) | Details |
15362974 | McNeill H, Knebel A, Arthur JS, Cuenda A, Cohen P: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. Biochem J. 2004 Dec 1;384(Pt 2):391-400. Termed SAKS1 (SAPK substrate-1), it was phosphorylated efficiently at Ser200 in vitro by SAPK3/p38gamma, SAPK4/p38delta and JNK (c-Jun N-terminal kinase), but weakly by SAPK2a/p38alpha, SAPK2b/p38beta2 or ERK (extracellular-signal-regulated kinase) 2. |
1(0,0,0,1) | Details |
12637567 | Kietzmann T, Samoylenko A, Immenschuh S: Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes. J Biol Chem. 2003 May 16;278(20):17927-36. Epub 2003 Mar 11. Heme oxygenase-1 (HO-1) gene expression is induced by various oxidative stress stimuli including sodium arsenite. |
0(0,0,0,0) | Details |