Name | ERK2 |
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Synonyms | ERK; P40; ERK 2; ERK2; ERT 1; ERT1; Extracellular signal regulated kinase 2; MAP kinase 2… |
Name | sodium arsenite |
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CAS | sodium arsenenite |
PubMed | Abstract | RScore(About this table) | |
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12482858 | Duyndam MC, Hulscher ST, van der Wall E, Pinedo HM, Boven E: Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite. J Biol Chem. 2003 Feb 28;278(9):6885-95. Epub 2002 Dec 13. By using kinase inhibitors in OVCAR-3 cells, both effects of sodium arsenite were found to be independent of phosphatidylinositol 3-kinase and p44/p42 MAPKS but were attenuated by inhibition of p38 MAPK. |
31(0,1,1,1) | Details |
7768904 | Trigon S, Morange M: Different carboxyl-terminal domain kinase activities are induced by heat-shock and arsenite. J Biol Chem. 1995 Jun 2;270(22):13091-8. We have previously shown that in HeLa cells a protein kinase (HS-CTD kinase) activity is induced rapidly after a heat or sodium arsenite shock. Mono Q chromatography allows the separation of five stress-induced CTD kinase activities, two of which coelute with active mitogen-activated protein kinase forms revealed by Western blotting with anti ERK1-ERK2 antibodies. |
2(0,0,0,2) | Details |
15362974 | McNeill H, Knebel A, Arthur JS, Cuenda A, Cohen P: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. Biochem J. 2004 Dec 1;384(Pt 2):391-400. Termed SAKS1 (SAPK substrate-1), it was phosphorylated efficiently at Ser200 in vitro by SAPK3/p38gamma, SAPK4/p38delta and JNK (c-Jun N-terminal kinase), but weakly by SAPK2a/p38alpha, SAPK2b/p38beta2 or ERK (extracellular-signal-regulated kinase) 2. |
1(0,0,0,1) | Details |
9671412 | Lim CP, Jain N, Cao X: Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1. Oncogene. 1998 Jun 4;16(22):2915-26. Here we report that in NIH3T3 cells, egr-1 is induced by various stress treatments such as heat shock, sodium arsenite, ultraviolet (U.V.) radiation, and anisomycin. p38 and JNK1, but not ERK2, were activated by these stress treatments. |
0(0,0,0,0) | Details |
12637567 | Kietzmann T, Samoylenko A, Immenschuh S: Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes. J Biol Chem. 2003 May 16;278(20):17927-36. Epub 2003 Mar 11. Heme oxygenase-1 (HO-1) gene expression is induced by various oxidative stress stimuli including sodium arsenite. |
0(0,0,0,0) | Details |