| Name | heat shock protein 27 |
|---|---|
| Synonyms | 28 kDa heat shock protein; CMT2F; Estrogen regulated 24 kDa protein; HS.76067; HSP 27; HSP27; HSP28; HSPB 1… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1939348 | Lee YJ, Curetty L, Corry PM: Differences in preferential synthesis and redistribution of HSP70 and HSP28 families by heat or sodium arsenite in Chinese hamster ovary cells. J Cell Physiol. 1991 Oct;149(1):77-87. |
34(0,1,1,4) | Details |
| 10841042 | Miwa M, Kozawa OO, Tokuda H, Uematsu T: Involvement of in chemical stress-induced interleukin-6 synthesis in osteoblast-like cells: comparison with heat shock protein 27 induction. Prostaglandins Leukot Essent Fatty Acids. 2000 Mar;62(3):189-93. In a previous study, we have demonstrated that sodium arsenite (arsenite) as chemical stress stimulates heat shock protein 27 (HSP27) induction and release in osteoblast-like MC3T3-E1 cells, and that the response of HSP27 induction is coupled with metabolic activity of the cascade. |
32(0,1,1,2) | Details |
| 2002259 | Edwards MJ, Marks R, Dykes PJ, Merrett VR, Morgan HE, O'Donovan MR: Heat shock proteins in cultured human keratinocytes and fibroblasts. . J Invest Dermatol. 1991 Mar;96(3):392-6. Exposure of these cells to weak inducing agents such as heat or cadmium sulphate resulted in the synthesis of HSP72 and HSP90, whereas HSP28 and HSP116 synthesis was detected in keratinocytes and fibroblasts following exposure to the strong inducing agent sodium arsenite. |
31(0,1,1,1) | Details |
| 11497330 | Kim D, Somji S, Garrett SH, Sens MA, Shukla D, Sens DA: Expression of hsp 27, hsp 60, hsc 70, and hsp 70 by immortalized human proximal tubule cells (HK-2) following exposure to heat shock, sodium arsenite, or cadmium J Toxicol Environ Health A. 2001 Aug 10;63(7):475-93. |
15(0,0,2,5) | Details |
| 12460802 | Rossi MR, Somji S, Garrett SH, Sens MA, Nath J, Sens DA: Expression of hsp 27, hsp 60, hsc 70, and hsp 70 stress response genes in cultured human urothelial cells (UROtsa) exposed to lethal and sublethal concentrations of sodium arsenite. Environ Health Perspect. 2002 Dec;110(12):1225-32. |
14(0,0,2,4) | Details |
| 8836877 | Suzuki A, Kozawa O, Oiso Y, Kato K: Protein kinase C activation inhibits stress-induced synthesis of heat shock protein 27 in osteoblast-like cells: function of J Cell Biochem. 1996 Jul;62(1):69-75. Exposure of osteoblast-like MC3T3-E1 cells to sodium arsenite (arsenite) increased the level of heat shock protein 27 (hsp27). |
7(0,0,1,2) | Details |
| 10379001 | Somji S, Sens DA, Garrett SH, Sens MA, Todd JH: Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCl2. Environ Health Perspect. 1999 Jul;107(7):545-52. Results were similar when the cells were subjected to chemical stress (exposure to 100 microM sodium arsenite for 4 hr). |
6(0,0,0,6) | Details |
| 17479414 | Yang P, He XQ, Peng L, Li AP, Wang XR, Zhou JW, Liu QZ: The role of oxidative stress in hormesis induced by sodium arsenite in human embryo lung fibroblast (HELF) cellular proliferation model. J Toxicol Environ Health A. 2007 Jun;70(11):976-83. Similarly, heat-shock protein 27 (HSP27) levels were increased by sodium arsenite of low concentrations with early exposure time (3, 6, and 12 h), but decreased with high metal concentrations with greater exposure time (24 and 48 h). |
6(0,0,1,1) | Details |
| 1618914 | Lee YJ, Hou ZZ, Curetty L, Borrelli MJ: Development of acute thermotolerance in L929 cells: lack of HSP28 synthesis and phosphorylation. J Cell Physiol. 1992 Jul;152(1):118-25. |
3(0,0,0,3) | Details |
| 11746514 | Tanabe K, Kozawa O, Niwa M, Yamomoto T, Matsuno H, Ito H, Kato K, Dohi S, Uematsu T: Contrasting effects of midazolam on induction of heat shock protein 27 by and heat in aortic smooth muscle cells. J Cell Biochem. 2001;84(1):39-46. In the present study, we examined the effects of midazolam, an intravenous anesthetic, on the HSP27 induction stimulated by heat, or sodium arsenite (arsenite) in A10 cells. |
2(0,0,0,2) | Details |
| 7851416 | Huot J, Lambert H, Lavoie JN, Guimond A, Houle F, Landry J: Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat-shock protein HSP27. Eur J Biochem. 1995 Jan 15;227(1-2):416-27. Heat-shock protein 27 (HSP27) is a major target of phosphorylation upon cell stimulation with a variety of agents and has been suggested to have a phosphorylation-regulated function at the level of actin filaments. The kinase activity in extracts of cells stimulated by heat shock, H2O2, sodium arsenite, TNF or growth factors was identified by in-gel renaturation and purified approximately 8000-fold by sequential chromatography. |
1(0,0,0,1) | Details |
| 11862762 | Kozawa O, Tokuda H: [Heat shock protein 27 in osteoblasts] . Nippon Yakurigaku Zasshi. 2002 Feb;119(2):89-94. Chemical stress by sodium arsenite (arsenite) induces HSP27 coupled to the metabolic activity of the cascade, and the HSP27 induction by arsenite is negatively regulated by activation of protein kinase C (PKC). |
1(0,0,0,1) | Details |
| 10923011 | Brophy CM, Molinaro JR, Dickinson M: The macromolecular associations of heat shock protein-27 in vascular smooth muscle. Surgery. 2000 Aug;128(2):320-6. |
1(0,0,0,1) | Details |
| 11698504 | Werz O, Klemm J, Radmark O, Samuelsson B: p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line. J Leukoc Biol. 2001 Nov;70(5):830-8. Here we demonstrate that several stimuli of cell stress such as osmotic shock NaCl), oxidative stress peroxide, diamide), chemical stress sodium arsenite, and inflammatory cytokines enhanced cellular 5-LO activity in a B cell line (BL41-E95-A), when added simultaneously with ionophore plus These stimuli also activated p38 mitogen-activated protein (MAP) kinase and downstream MAP kinase-activated protein kinases in BL41-E95-A cells, which could phosphorylate 5-LO or heat shock protein 27 in vitro. |
1(0,0,0,1) | Details |