| Name | adenylate cyclase |
|---|---|
| Synonyms | AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1018066 | Spiegel AM, Brown EM, Aurbach GD: Inhibition of adenylate cyclase by arsenite and cadmium: evidence for a vicinal dithiol requirement. J Cyclic Nucleotide Res. 1976 Nov-Dec;2(6):393-404. Sodium arsenite was a weak inhibitor of adenylate cyclase -7mM produced only 60% inhibition. |
331(4,4,5,6) | Details |
| 15906006 | Willemsen P, Scippo ML, Maghuin-Rogister G, Martial JA, Muller M: Enhancement of steroid receptor-mediated transcription for the development of highly responsive bioassays. Anal Bioanal Chem. 2005 Jun;382(4):894-905. Epub 2005 May 20. Sodium arsenite-induced chemical stress leads to a substantial and specific increase in the glucocorticoid receptor-mediated transcription, resulting in maximal stimulations of more than 2000-fold by the agonist dexamethasone. Similarly, a combined treatment with forskolin (an activator of adenylate cyclase) and trichostatin A (an inhibitor of histone deacetylases) leads to a synergistic enhancement of or androgen stimulation, resulting in a maximal induction of more than 200-fold or about 100-fold, respectively. |
1(0,0,0,1) | Details |