Protein Information

Name HSP47
Synonyms 47 kDa heat shock protein; Arsenic transactivated protein 3; AsTP3; CBP 1; CBP 2; CBP1; CBP2; Collagen binding protein 1…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
2256819 Sauk JJ, Norris K, Moehring J, Foster RA, Somerman MJ: The expression of colligin/hsp47 after stress in human periodontal fibroblasts in vitro. Arch Oral Biol. 1990;35(8):645-51.

These studies showed that (a) sodium arsenite and AZC enhanced the cellular levels of hsp47 in both types of fibroblast, (b) the colligin/hsp47 levels expressed were associated with elevated levels of protein and collagen production and (c) the presence of colligin/hsp47 was decreased under conditions of serum deprivation.
83(1,1,1,3) Details
8187816 Kudo H, Hirayoshi K, Kitagawa Y, Imamura S, Nagata K: Two collagen-binding proteins, osteonectin and HSP47, are coordinately induced in transformed keratinocytes by heat and other stresses. Exp Cell Res. 1994 Jun;212(2):219-24.

Both the mRNA levels and the secretion of osteonectin increased concurrently when Pam and HSC-1 cells cultured in low calcium medium were exposed to various stresses including heat shock and treatment with sodium arsenite or L-azetidine-2-carboxylic acid.
4(0,0,0,4) Details
8264624 Takechi H, Hosokawa N, Hirayoshi K, Nagata K: Alternative 5' splice site selection induced by heat shock. Mol Cell Biol. 1994 Jan;14(1):567-75.

The mouse HSP47 gene consists of six exons separated by five introns.
Other stress inducers, including an amino acid analog and sodium arsenite, had no effect on the alternative splicing.
2(0,0,0,2) Details
7747457 Andrews JM, Oglesbee MJ, Trevino AV, Guyot DJ, Newbound GC, Lairmore MD: Enhanced human T-cell lymphotropic virus type I expression following induction of the cellular stress response. Virology. 1995 Apr 20;208(2):816-20.


Induction of the cellular stress response in HTLV-I-infected lymphocytes resulted in significantly increased HTLV-I-mediated syncytia formation due to enhanced HTLV-I envelope (gp46) expression.
1(0,0,0,1) Details