Protein Information

Name protein phosphatase
Synonyms DUSP17; DUSP19; Dual specificity phosphatase 19; Dual specificity protein phosphatase 19; Dual specificity phosphatase TS DSP1; LMW DSP3; Protein phosphatase; Protein phosphatase SKRP1…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
7737136 Huang RN, Ho IC, Yih LH, Lee TC: Sodium arsenite induces chromosome endoreduplication and inhibits protein phosphatase activity in human fibroblasts. Environ Mol Mutagen. 1995;25(3):188-96.
162(2,2,2,2) Details
7858064 Vietor I, Vilcek J: Pathways of heat shock protein 28 phosphorylation by TNF in human fibroblasts. Lymphokine Cytokine Res. 1994 Oct;13(5):315-23.

The finding that sodium arsenite strongly increased Hsp28 phosphorylation, together with the resistance of TNF-induced phosphorylation to kinase inhibitors, supports the notion that increased serine phosphorylation of Hsp28 in this system involves inhibition of protein phosphatase activity.
81(1,1,1,1) Details