| Name | NF kappa B |
|---|---|
| Synonyms | DNA binding factor KBF1; EBP 1; KBF 1; KBF1; NF kappa B; NFKB p105; NFKB p50; NFKB 1… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12076508 | Hu Y, Jin X, Snow ET: Effect of arsenic on transcription factor AP-1 and NF-kappaB DNA binding activity and related gene expression. Toxicol Lett. 2002 Jul 7;133(1):33-45. Both acute (24 h) and chronic (10-20 week) exposure of human fibroblast cells to low dose sodium arsenite (As (III)) significantly affects activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) DNA binding activity. |
35(0,1,1,5) | Details |
| 14962100 | Liao WT, Chang KL, Yu CL, Chen GS, Chang LW, Yu HS: Arsenic induces human keratinocyte apoptosis by the FAS/FAS ligand pathway, which correlates with alterations in nuclear factor-kappa B and activator protein-1 activity. J Invest Dermatol. 2004 Jan;122(1):125-9. To investigate the mechanism of arsenic-induced apoptosis and related alterations in NF-kappa B and AP-1 activity, we exposed cultured human foreskin keratinocytes to different concentrations of sodium arsenite. |
34(0,1,1,4) | Details |
| 10896383 | Pritts TA, Wang Q, Sun X, Moon MR, Fischer DR, Fischer JE, Wong HR, Hasselgren PO: Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice. Arch Surg. 2000 Jul;135(7):860-6. The transcription factor nuclear factor-kappa B (NF-kappa B), normally sequestered in the cytoplasm by its inhibitory protein, I kappa B, regulates many genes involved in inflammatory responses to critical illness. METHODS: The stress response was induced in mice by hyperthermia (42 degrees C) or injection with sodium arsenite (10 mg/kg). |
4(0,0,0,4) | Details |
| 12210719 | Li M, Cai JF, Chiu JF: Arsenic induces oxidative stress and activates stress gene expressions in cultured lung epithelial cells. J Cell Biochem. 2002;87(1):29-38. Responsiveness of LEC to oxidative stress caused by arsenic exposure was further evaluated with mobility shift assay involving redox-sensitive transcription factor NF-kappa B. |
3(0,0,0,3) | Details |
| 8902524 | Barchowsky A, Dudek EJ, Treadwell MD, Wetterhahn KE: Arsenic induces oxidant stress and NF-kappa B activation in cultured aortic endothelial cells. Free Radic Biol Med. 1996;21(6):783-90. |
3(0,0,0,3) | Details |
| 10799907 | Yoo CG, Lee S, Lee CT, Kim YW, Han SK, Shim YS: Anti-inflammatory effect of heat shock protein induction is related to stabilization of I kappa B alpha through preventing I kappa B kinase activation in respiratory epithelial cells. J Immunol. 2000 May 15;164(10):5416-23. Because HSP induction inhibits genetic expression of pro-inflammatory cytokines, the transcription of which is dependent on NF-kappa B activation, we explored the relationship between the anti-inflammatory effect of HSP induction and the NF-kappa B/I kappa B alpha pathway. Both HS and sodium arsenite treatment increased HSP70 expression time dependently at mRNA and protein levels. |
2(0,0,0,2) | Details |
| 19616567 | Ghosh J, Das J, Manna P, Sil PC: prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-kappa B, p38 and JNK MAPK pathway. Toxicol Appl Pharmacol. 2009 Oct 1;240(1):73-87. Epub 2009 Jul 17. |
1(0,0,0,1) | Details |
| 15849723 | Felix K, Manna SK, Wise K, Barr J, Ramesh GT: Low levels of arsenite activates nuclear factor-kappaB and activator protein-1 in immortalized mesencephalic cells. J Biochem Mol Toxicol. 2005 Mar-Apr;19(2):67-77. N-acetyl- at 50 microM concentration inhibited arsenite-induced NF-kappa B and AP-1. These mesencephalic cells were treated with low concentrations of sodium arsenite (0.1, 0.5, 1, 5, and 10 microM) and incubated for different periods of time (0-4 h). |
1(0,0,0,1) | Details |