| Name | cyclin B1 |
|---|---|
| Synonyms | CCNB; CCNB 1; CCNB1; Cyclin B1; G2/mitotic specific cyclin B1; Cyclin B1s; G2/mitotic specific cyclin B1s |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17373649 | Li JP, Yang JL: Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite. J Cell Physiol. 2007 Aug;212(2):481-8. |
11(0,0,0,11) | Details |
| 11721386 | Ma D, Sun Y, Ma X: [Sodium arsenite selectively inducing apoptosis of G2 + M phase NB4 cells] . Zhonghua Xue Ye Xue Za Zhi. 1999 Jun;20(6):296-9. CONCLUSION: Sodium arsenite selectively induced apoptosis of G2 + M phase NB4 cells, accompanied by upregulation of cyclin B1. |
7(0,0,1,2) | Details |
| 15476864 | Zhou H, Kato A, Yasuda H, Miyaji T, Fujigaki Y, Yamamoto T, Yonemura K, Hishida A: The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure. Toxicol Appl Pharmacol. 2004 Oct 15;200(2):111-20. The expressions of cyclin-dependent kinase inhibitors (p21 and p27), cyclin B1, cyclin D1, PCNA, GADD 45, and GADD 153 were significantly increased in the outer medulla, reaching peak levels at 3 days after CDDP. Sodium arsenite (SA), a heavy metal, attenuated tubular damage and increased Scr- and TUNEL-positive cells at 5 days after CDDP. |
3(0,0,0,3) | Details |
| 9371502 | Yih LH, Ho IC, Lee TC: Sodium arsenite disturbs mitosis and induces chromosome loss in human fibroblasts. Cancer Res. 1997 Nov 15;57(22):5051-9. Arsenite-induced G2 and mitotic delay are accompanied by accumulation of cyclin B1 and hyperphosphorylation of cdc2 and Mos proteins. |
1(0,0,0,1) | Details |
| 16338954 | Chao JI, Hsu SH, Tsou TC: Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway. Toxicol Sci. 2006 Mar;90(1):73-86. Epub 2005 Dec 7. In this study, the effects of sodium arsenite on the expression of securin in two tissue types of cell lines, the vascular endothelial and colorectal epithelial cells, were investigated. The levels of phospho-CDC2 -161), CDC2, and cyclin B1 proteins were decreased, and the G2/M fractions were increased by arsenite. |
1(0,0,0,1) | Details |