Protein Information

Name serine threonine protein kinase
Synonyms PKU BETA; Protein serine/threonine kinase; PKUb; PKUbeta; Protein kinase ubiquitous beta; Serine threonine protein kinase; Serine threonine protein kinase tousled like 1; TLK 1…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
9837746 Kitagawa M, Mukai H, Takahashi M, Ono Y: The role of PKN in the regulation of alphaB-crystallin expression via heat shock transcription factor 1. Biochem Biophys Res Commun. 1998 Nov 27;252(3):561-5.

We previously reported that PKN, a fatty acid-activated serine/threonine protein kinase, translocates from the cytosol to the nucleus by stresses such as heat shock, sodium arsenite, and serum starvation.
31(0,1,1,1) Details
16256366 Zhao Q, Chen P, Manson ME, Liu Y: Production of active recombinant mitogen-activated protein kinases through transient transfection of 293T cells. Protein Expr Purif. 2006 Apr;46(2):468-74. Epub 2005 Oct 10.

Mitogen-activated protein (MAP) kinases are a family of serine/threonine protein kinases that play an important role in a myriad of cellular processes, including cell proliferation, differentiation, and apoptosis.
The protein kinases were activated in vivo through treating the transfected cells with sodium arsenite and affinity-purified using glutathione-Sepharose beads.
1(0,0,0,1) Details