| Name | Raf 1 |
|---|---|
| Synonyms | C RAF; CRAF; Oncogene MIL; Oncogene RAF1; RAF; RAF proto oncogene serine/threonine protein kinase; RAF1; RAF1 protein… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11160250 | Chakravortty D, Kato Y, Sugiyama T, Koide N, Mu MM, Yoshida T, Yokochi T: The inhibitory action of sodium arsenite on lipopolysaccharide-induced production in RAW 267.4 macrophage cells: a role of Raf-1 in lipopolysaccharide signaling. J Immunol. 2001 Feb 1;166(3):2011-7. |
83(1,1,1,3) | Details |
| 8556709 | Kim SH, Lee SH, Kwak NH, Kang CD, Chung BS: Effect of the activated Raf protein kinase on the human multidrug resistance 1 (MDR1) gene promoter. Cancer Lett. 1996 Jan 2;98(2):199-205. Using MDR1 deletion constructs and the 22W mutant of c-Raf in which the NH2-terminal half has been deleted, we examined the effect of the activated Raf on human MDR1 promoter activity in transient expression assay and stable transfectants of GHE-L cells. We observed that the activated Raf significantly potentiated the induction of MDRCAT activity in GHE-L cells by sodium arsenite or heat shock, which stimulates heat shock factor (HSF) binding to HSE. |
1(0,0,0,1) | Details |
| 12637567 | Kietzmann T, Samoylenko A, Immenschuh S: Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes. J Biol Chem. 2003 May 16;278(20):17927-36. Epub 2003 Mar 11. Heme oxygenase-1 (HO-1) gene expression is induced by various oxidative stress stimuli including sodium arsenite. |
0(0,0,0,0) | Details |
| 9671310 | Doza YN, Hall-Jackson CA, Cohen P: Arsenite blocks growth factor induced activation of the MAP kinase cascade, upstream of Ras and downstream of Grb2-Sos. Oncogene. 1998 Jul 9;17(1):19-24. Pretreatment of cells with 0.5 mM sodium arsenite (but not other activators of stress-activated MAP kinase cascades) prevents the activation of p21Ras and strongly suppresses the activation of c-Raf and the MAP kinase cascade by a variety of growth factors. |
0(0,0,0,0) | Details |