Protein Information

Name MGST1
Synonyms GST12; Glutathione S transferase 12; MGST; MGST 1; MGST I; MGST1; MGST1 protein; Microsomal GST 1…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
16125204 Shinno E, Shimoji M, Imaizumi N, Kinoshita S, Sunakawa H, Aniya Y: Activation of rat liver microsomal glutathione S-transferase by gallic acid. Life Sci. 2005 Nov 19;78(1):99-106. Epub 2005 Aug 25.

The effect of phenolic antioxidants on the rat liver microsomal glutathione S-transferase (MGST1) was investigated in vitro.
The MGST1 activity increased by gallic acid was decreased by further incubation with sodium arsenite, a sulfenic acid reducing agent, but was not with dithiothreitol, a disulfide bond reducing agent.
4(0,0,0,4) Details
16386761 Imaizumi N, Miyagi S, Aniya Y: Reactive nitrogen species derived activation of rat liver microsomal glutathione S-transferase. Life Sci. 2006 May 22;78(26):2998-3006. Epub 2006 Jan 4.

MGST1 activity was increased by ONOO (-) in the presence of high amounts of reducing agents including glutathione (GSH) and the activities increased by ONOO (-) or ONOO (-) plus GSH treatment were decreased by 30-40% by further incubation with dithiothreitol (DTT, reducing disulfide) or by sodium arsenite (reducing sulfenic acid).
36(0,1,1,6) Details