Protein Information

Name Protein S
Synonyms PROS; PSA; PROS 1; PROS 2; PROS1; PROS2; PROSP; PS 26…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
2777774 Disa S, Manilla AC, Scher CD: Purification and characterization of a platelet-derived growth factor and heavy metal-modulated nuclear protein. J Biol Chem. 1989 Sep 25;264(27):15993-9.

Platelet-derived growth factor (PDGF), fibroblast growth factor, and heavy metal salts such as sodium arsenite stimulated BALB/c-3T3 cells to synthesize a 31-kDa protein (s) (termed p31) in a concentration-dependent manner. p31 was also synthesized in response to 12-O-tetradecanoylphorbol-13-acetate (TPA).
81(1,1,1,1) Details
2469684 Edington BV, Whelan SA, Hightower LE: Inhibition of heat shock (stress) protein induction by deuterium oxide and glycerol: additional support for the abnormal protein hypothesis of induction. J Cell Physiol. 1989 May;139(2):219-28.

Evidence that the heat-sensitive target (s) is likely to be a protein (s) is summarized.
This result and the fact that the chemical stressor sodium arsenite induced stress proteins in glycerol medium indicated that the treatments did not irreversibly inhibit the induction pathways and that the stress response could be triggered even in the presence of glycerol by a stressor other than heat.
1(0,0,0,1) Details
16283521 Othumpangat S, Kashon M, Joseph P: Sodium arsenite-induced inhibition of eukaryotic translation initiation factor 4E (eIF4E) results in cytotoxicity and cell death. Mol Cell Biochem. 2005 Nov;279(1-2):123-31.

Immunoprecipitation of lysates obtained from the NaAsO2-treated cells and the subsequent western blot analysis of the immunoprecipitated protein (s) using the eIF4E antibody detected the presence of eIF4E protein in the immunoprecipitate suggesting possible ubiquitination of eIF4E protein in the NaAsO2-treated cells.
1(0,0,0,1) Details