| Name | TRAIL |
|---|---|
| Synonyms | APO2L; Apo 2 ligand; Apo 2L; CD253; CD253 antigen; Protein TRAIL; TL2; TNF related apoptosis inducing ligand… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17070520 | Ivanov VN, Hei TK: Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. Exp Cell Res. 2006 Dec 10;312(20):4120-38. Epub 2006 Sep 28. |
95(0,3,3,5) | Details |
| 17545621 | Ivanov VN, Zhou H, Hei TK: Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res. 2007 Jun 1;67(11):5397-407. |
39(0,1,2,4) | Details |
| 18222423 | Ivanov VN, Partridge MA, Johnson GE, Huang SX, Zhou H, Hei TK: sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Exp Cell Res. 2008 Mar 10;314(5):1163-76. Epub 2007 Dec 23. Interestingly, did not increase surface expression of DR5 in human melanomas, while gamma-irradiation or sodium arsenite treatment substantially upregulated DR5 expression. |
6(0,0,0,6) | Details |
| 15741166 | Miralem T, Hu Z, Torno MD, Lelli KM, Maines MD: Small interference RNA-mediated gene silencing of human reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. J Biol Chem. 2005 Apr 29;280(17):17084-92. Epub 2005 Feb 28. The presence of BVR small interference RNA augmented the effect of As on levels of cytochrome c, TRAIL, and DR-5 mRNA and cleavage of poly (ADP- polymerase. Presently, small interference (si) RNA constructs were used to investigate the role of human BVR in sodium arsenite (As)-mediated induction of HO-1 and in cytoprotection against apoptosis. |
1(0,0,0,1) | Details |