Protein Information

Name protoporphyrinogen oxidase
Synonyms Mutant protoporphyrinogen oxidase; VP; PPO; PPOX; Protoporphyrinogen oxidase; V290M; Protoporphyrinogen oxidases

Compound Information

Name sulfentrazone
CAS

Reference List

PubMed Abstract RScore(About this table)
18943113 Daugrois JH, Hoy JW, Griffin JL: Protoporphyrinogen oxidase inhibitor herbicide effects on pythium root rot of sugarcane, pythium species, and the soil microbial community. Phytopathology. 2005 Mar;95(3):220-6.

ABSTRACT The effects of three protoporphyrinogen oxidase inhibitor herbicides, azafenidin, flumioxazin, and sulfentrazone, on Pythium root rot of sugarcane and the soil microbial community were evaluated in greenhouse experiments.
32(0,1,1,2) Details
10432190 Carre J, Eleouet S, Rousset N, Vonarx V, Heyman D, Lajat Y, Patrice T: Protoporphyrin IX fluorescence kinetics in C6 glioblastoma cells after delta-aminolevulinic acid incubation: effect of a protoporphyrinogen oxidase inhibitor. Cell Mol Biol (Noisy-le-grand). 1999 Jun;45(4):433-44.

To perform this experiment we used confocal microspectrofluorometry to analyse the effects of a highly purified form of sulfentrazone (FP846) on the kinetics of PpIX synthesis after ALA administration to living C6 cells.
1(0,0,0,1) Details
18298068 Luo YP, Jiang LL, Wang GD, Chen Q, Yang GF: Syntheses and herbicidal activities of novel triazolinone derivatives. . J Agric Food Chem. 2008 Mar 26;56(6):2118-24. Epub 2008 Feb 26.

Protoporphyrinogen oxidase (Protox, EC 1.3.3.4) has been identified as one of the most important action targets of herbicides.
Most fortunately, compound 3, methyl 2-[3-methyl-(2-fluoro-4-chloro-5-ethylsulfonamidephenyl)-4,5-dihydro-5-oxo -1 H-1,2,4-triazol-4-yl] methylenephenyl-2-( E)-methoxyiminoacetate, was found to be the most promising candidate due to its comparable herbicidal activity at 75-150 g of active ingredient/ha with the commercial product sulfentrazone.
1(0,0,0,1) Details