Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name butachlor
CAS

Reference List

PubMed Abstract RScore(About this table)
1728663 Ou YH, Lin JK: Biotransformation of butachlor through mercapturic acid pathway in rat tissue homogenates. J Toxicol Environ Health. 1992 Jan;35(1):19-28.

These findings demonstrated that butachlor is initially conjugated with GSH to form BGSC by the enzyme glutathione S-transferase in the liver.
82(1,1,1,2) Details
16835885 Scarponi L, Quagliarini E, Del Buono D: Induction of wheat and maize glutathione S-transferase by some herbicide safeners and their effect on enzyme activity against butachlor and terbuthylazine. Pest Manag Sci. 2006 Oct;62(10):927-32.
7(0,0,1,2) Details
20183093 Scarponi L, Del Buono D: Festuca arundinacea, glutathione S-transferase and herbicide safeners: a preliminary case study to reduce herbicidal pollution. J Environ Sci Health B. 2009 Nov;44(8):805-9.

Assays of GST activity towards the herbicides terbuthylazine (N (2)-tert-butyl-6-chloro-N (4)-ethyl-1,3,5-triazine-2,4-diamine) and butachlor (N-butoxymethyl-2-chloro-2',6'-diethylacetanilide) as substrates also showed the ability of the safeners to enhance the enzyme activity towards both these herbicides, with the exception of cloquintocet-mexyl for the enzyme activity towards butachlor.
2(0,0,0,2) Details
9879635 Ishizuka M, Iwata H, Kazusaka A, Hatakeyama S, Fujita S: Effects of the agrochemicals butachlor, pretilachlor and isoprothiolane on rat liver xenobiotic-metabolizing enzymes. Xenobiotica. 1998 Nov;28(11):1029-39.

We administered these agrochemicals to the male rat and examined their effects on cytochrome P450 (P450), glutathione S-transferase (GST), UDP-glucuronosyltransferase (UDPGT), and NAD (P) H-quinone oxidoreductase 1 (NQO1)-related metabolism in the liver. 2.
1(0,0,0,1) Details