| Name | catalase |
|---|---|
| Synonyms | CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases… |
| Name | 2,4-D |
|---|---|
| CAS | 2-(2,4-dichlorophenoxy)acetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15485668 | Teixeira MC, Telo JP, Duarte NF, Sa-Correia I: The herbicide 2,4-dichlorophenoxyacetic acid induces the generation of free-radicals and associated oxidative stress responses in yeast. Biochem Biophys Res Commun. 2004 Nov 19;324(3):1101-7. The pro-oxidant action of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is demonstrated in this study using Saccharomyces cerevisiae as a eukaryotic experimental model. The variation pattern of the level of adducts correlated with the one determined for the activity of Sod1p, cytosolic catalase Ctt1p, and the dithiol glutaredoxins Grx1p and Grx2p. |
1(0,0,0,1) | Details |
| 1777922 | Cherkaoui Malki M, Assaka L, Pacot C, Bardot O, Latruffe N: Effect of different hypolipemic agents on rat liver peroxisomal and mitochondrial functions and biogenesis. Cell Mol Biol. 1991;37(7):723-33. The effect of four fibrate analogues (i.e. clofibrate, ciprofibrate, clobuzarit and 2,4-dichlorophenoxyacetic acid (2,4-D), an active herbicide molecule) were tested on the biogenesis of liver mitochondrial and peroxisomal proteins by rat in vivo treatment at 100 ppm for 26 weeks. Post-transcriptional study of mRNAs level shows a slight increase in catalase mRNA despite the potential of hypolipemic agents. |
1(0,0,0,1) | Details |
| 20112812 | Rajab R, Rajan SS, Satheesh LS, Harish SR, Sunukumar SS, Sandeep BS, Mohan TC, Murugan K: Hypersensitive response of Sesamum prostratum Retz. elicitated by Fusarium oxysporum f. sesame (Schelt) Jacz Butler. Indian J Exp Biol. 2009 Oct;47(10):834-8. Aim of this study was to investigate the intensity and timing of the ROS formation, lipid peroxidation and expression of antioxidant enzymes as initial responses of calli of Sesamum prostratum (SP) against Fusarium oxysporum f. sesame crude toxin metabolite of varying concentrations. 2,4 dichlorophenoxy (2,4-D) / coconut milk combinations were found to be more efficient among different hormonal regimes (2,4 -D, 2,4-D/casein hydrosylate and 2,4-D/ coconut milk). The poor activity of catalase confirmed the oxidative burst in the callus leading to necrosis. |
1(0,0,0,1) | Details |
| 12242687 | Oruc EO, Uner N: Marker enzyme assessment in the liver of cyprinus carpio (L.) exposed to 2,4-D and azinphosmethyl. J Biochem Mol Toxicol. 2002;16(4):182-8. Glutathione reductase and catalase enzyme activities, and malondialdehyde levels remained constant in all the treatment groups compared with controls. |
1(0,0,0,1) | Details |
| 18436336 | Peixoto FP, Gomes-Laranjo J, Vicente JA, Madeira VM: Comparative effects of the herbicides dicamba, 2,4-D and paraquat on non-green potato tuber calli. J Plant Physiol. 2008 Jul 31;165(11):1125-33. Epub 2008 Apr 23. Paraquat induced catalase (CAT) activity at low concentrations (1 microM), whereas at higher concentrations, inhibition was observed. |
1(0,0,0,1) | Details |
| 6626247 | Vainio H, Linnainmaa K, Kahonen M, Nickels J, Hietanen E, Marniemi J, Peltonen P: Hypolipidemia and peroxisome proliferation induced by phenoxyacetic acid herbicides in rats. Biochem Pharmacol. 1983 Sep 15;32(18):2775-9. A hypolipidemic drug, clofibrate [ethyl-2-(4-chlorophenoxy)- which is structurally related to phenoxy acids, was used as a positive control (200 mg/kg body wt). 2,4-D and MCPA had several effects similar to those of clofibrate: all three compounds induced proliferation of hepatic peroxisomes, decreased serum lipid levels, and increased hepatic carnitine acetyltransferase and catalase activities. 2,4-D and MCPA, but not clofibrate, decreased lipoprotein lipase activity in the adipose tissue to about a third of the control value but did not change the lipoprotein lipase activity in the heart muscle. |
0(0,0,0,0) | Details |
| 11023648 | Bukowska B, Chajdys A, Duda W, Duchnowicz P: Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites. Cell Biol Int. 2000;24(10):705-11. The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1. 6- peroxide: peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2, 4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory. |
1(0,0,0,1) | Details |
| 6704149 | Kawashima Y, Katoh H, Nakajima S, Kozuka H, Uchiyama M: Effects of 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid on peroxisomal enzymes in rat liver. Biochem Pharmacol. 1984 Jan 15;33(2):241-5. The effects of feeding 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) on the level of peroxisomal enzymes in rat liver were studied. The concentration of triglyceride in serum was decreased and the activity of -insensitive oxidation, catalase and carnitine acetyltransferase increased. |
1(0,0,0,1) | Details |
| 11246500 | Oruc EO, Uner N: Combined effects of 2,4-D and azinphosmethyl on antioxidant enzymes and lipid peroxidation in liver of Oreochromis niloticus. Comp Biochem Physiol C Toxicol Pharmacol. 2000 Dec;127(3):291-6. |
0(0,0,0,0) | Details |
| 2048162 | Gallagher EP, Di Giulio RT: Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). Toxicol Lett. 1991 Jun;57(1):65-72. Channel catfish (Ictalurus punctatus) exposed to a mixture of picloram and 2,4-dichlorophenoxyacetic acid (2,4-D) for 10 days displayed increased activities of hepatic ethoxyresorufin O-deethylase (EROD), decreased serum concentrations and decreased liver/body weight ratios. |
0(0,0,0,0) | Details |
| 3923930 | Amy PS, Schulke JW, Frazier LM, Seidler RJ: Characterization of aquatic bacteria and cloning of genes specifying partial degradation of 2,4-dichlorophenoxyacetic acid. Appl Environ Microbiol. 1985 May;49(5):1237-45. samples from rivers, streams, ponds, and activated sewage were tested for the presence of bacteria which utilize 2,4-dichlorophenoxyacetic acid (2,4-D) as a sole source of carbon. |
0(0,0,0,0) | Details |
| 11560249 | Ozaki K, Mahler JF, Haseman JK, Moomaw CR, Nicolette ML, Nyska A: Unique renal tubule changes induced in rats and mice by the peroxisome proliferators 2,4-dichlorophenoxyacetic acid (2,4-D) and WY-14643. Toxicol Pathol. 2001 Jul-Aug;29(4):440-50. |
0(0,0,0,0) | Details |
| 2225320 | Abdellatif AG, Preat V, Vamecq J, Nilsson R, Roberfroid M: Peroxisome proliferation and modulation of rat liver carcinogenesis by 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxyacetic acid, perfluorooctanoic acid and nafenopin. Carcinogenesis. 1990 Nov;11(11):1899-902. In comparison with controls, NAF and PFOA caused a 60-and 24-fold increase inthe peroxisomal beta-oxidation of fatty acids respectively, but only about a 2-fold increase in the catalase activity, 2,4-D and/or 2,4,5-T were much less active in this respect, giving approximately a doubling in the rate of fatty acid oxidation. |
31(0,1,1,1) | Details |
| 2334865 | Mikalsen SO, Holen I, Sanner T: Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and sulphate. Cell Biol Toxicol. 1990 Jan;6(1):1-13. The abilities of the hepatic peroxisome proliferators (HPPs) clofibrate, di (2-ethylhexyl) (DEHP), mono (2-ethylhexyl)- (MEHP), 2,4-dichlorophenoxy (2,4-D), 2,4,5-trichlorophenoxy (2,4,5-T) and tiadenol to induce morphological transformation and to increase the catalase activity of Syrian hamster embryo (SHE) cells were studied. |
11(0,0,1,6) | Details |
| 1628858 | Jacobi H, Metzger J, Witte I: Synergistic effects of Cu (II) and dimethylammonium 2,4-dichlorophenoxyacetate (U46 D fluid) on PM2 DNA and mechanism of DNA damage. Free Radic Res Commun. 1992;16(2):123-30. So did catalase (up to 100 mM 2,4-D . |
6(0,0,1,1) | Details |
| 17449452 | Bongiovanni B, De Lorenzi P, Ferri A, Konjuh C, Rassetto M, Evangelista de Duffard AM, Cardinali DP, Duffard R: decreases the oxidative stress produced by 2,4-dichlorophenoxyacetic acid in rat cerebellar granule cells. Neurotox Res. 2007 Feb;11(2):93-9. Cellular viability, generation of reactive species (ROS) and reactive species (RNS), (GSH) levels, and the activities of the antioxidant enzymes Cu/Zn-superoxide dismutase (Cu/Zn-SOD), Mn-SOD, - peroxidase (Se-GPx) and catalase (CAT) were measured in CGC exposed to 2,4-D and/or for 48 h. |
6(0,0,1,1) | Details |
| 16906522 | Celik I, Tuluce Y, Isik I: Influence of subacute treatment of some plant growth regulators on serum marker enzymes and erythrocyte and tissue antioxidant defense and lipid peroxidation in rats. J Biochem Mol Toxicol. 2006;20(4):174-82. This study aims to investigate the effects of the plant growth regulators (PGRs) (2,3,5-triiodobenzoic acid (TIBA), Naphthaleneacetic acid (NAA), and 2,4-dichlorofenoxyacetic acid (2,4-D)) on serum marker enzymes (aspartate aminotransferase (AST), alanin aminotransferase (ALT), phosphokinase (CPK), and lactate dehydrogenase (LDH)), antioxidant defense systems (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST), and catalase (CAT)), and lipid peroxidation content (malondialdehyde = MDA) in various tissues of rats. 50 and 100 ppm of PGRs as drinking water were administered orally to rats (Sprague-Dawley albino) ad libitum for 25 days continuously. |
6(0,0,1,1) | Details |
| 18000851 | Celik I, Tuluce Y: Determination of toxicity of subacute treatment of some plant growth regulators on rats. Environ Toxicol. 2007 Dec;22(6):613-9. The effects of some plant growth regulators (PGRs), 2,3,5-triiodobenzoic acid (TIBA), Naphthaleneacetic acid (NAA) and 2,4-Dichlorofenoxyacetic acid (2,4-D), at sublethal concentrations on antioxidant defense system peroxidases (GPx), (GSH), glutathione reductase (GR), glutathione-S-transferase (GST) and catalase (CAT)], immune potential enzymes [adenosine deaminase (ADA) and myeloperoxidase (MPO)], and lipid peroxidation content [Malondialdehyde, (MDA)] were investigated in lung and speen tissues of rats. |
6(0,0,1,1) | Details |
| 2306265 | Mikalsen SO, Ruyter B, Sanner T: Effects of hepatic peroxisome proliferators and 12-O-tetradecanoyl phorbol-13- on catalase and other enzyme activities of embryonic cells in vitro. Biochem Pharmacol. 1990 Feb 1;39(3):527-35. The effects of the hepatic peroxisome proliferators (HPPs) clofibrate, di-(2-ethylhexyl)- (DEHP), mono-(2-ethylhexyl) (MEHP) and 2,4-dichlorophenoxy (2,4-D) on the activities of some peroxisome-associated enzymes and marker enzymes for other organelles, have been studied in primary Syrian hamster embryo (SHE) cells and Wistar rat embryo (WRE) cells. |
4(0,0,0,4) | Details |
| 14984703 | Oruc EO, Sevgiler Y, Uner N: Tissue-specific oxidative stress responses in fish exposed to 2,4-D and azinphosmethyl. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Jan;137(1):43-51. Superoxide dismutase (SOD), peroxidase (GPx) and catalase activities were monitored in kidney, brain and gill. |
3(0,0,0,3) | Details |
| 8368864 | Evangelista de Duffard AM, Fabra de Peretti A, Castro de Cantarini S, Duffard R: Effects of 2,4-dichlorophenoxyacetic acid butyl ester on chick liver. . Arch Environ Contam Toxicol. 1993 Aug;25(2):204-11. Fertilized hen eggs were externally treated with 3.1 mg 2,4-dichlorophenoxyacetic acid butyl ester (2,4-D ester) before starting incubation. Furthermore, catalase, glutathione S-transferase and glucose 6-phosphatase activities as well as content were determined. |
2(0,0,0,2) | Details |
| 17582670 | Dinamarca VM, Hidalgo ME, Cavieres MF: Lack of effects of 2,4-dichlorophenoxyacetic acid administration on markers of oxidative stress during early pregnancy in mice. Toxicology. 2007 Jul 31;237(1-3):104-10. Epub 2007 May 6. Induction of oxidative stress by 2,4-dichlorophenoxyacetic acid (2,4-D) both as a pure compound and in commercial formulation was investigated during early pregnancy in mice. Pregnant animals were exposed to increasing doses of the herbicide (0.01, 0.1 and 100mg/kg/d) during gestation days 0-9, after which animals were euthanized and their blood analyzed for catalase activity, thiobarbituric acid reactive substances (TBARs) and total antioxidant capacity (TAC). |
1(0,0,0,1) | Details |