| Name | MAPK (protein family or complex) |
|---|---|
| Synonyms | MAPK; mitogen activated protein kinase; mitogen activated protein kinases |
| Name | 2,4-D |
|---|---|
| CAS | 2-(2,4-dichlorophenoxy)acetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17055699 | LaChapelle AM, Ruygrok ML, Toomer M, Oost JJ, Monnie ML, Swenson JA, Compton AA, Stebbins-Boaz B: The hormonal herbicide, 2,4-dichlorophenoxyacetic acid, inhibits Xenopus oocyte maturation by targeting translational and post-translational mechanisms. Reprod Toxicol. 2007 Jan;23(1):20-31. Epub 2006 Sep 9. RNA analysis showed -induced polyadenylation as expected but none with 2,4-D. 2,4-D-activated MAPK was determined to be cytoplasmic in localization studies but poorly induced Rsk2 phosphorylation and activation. |
81(1,1,1,1) | Details |
| 14694440 | Stebbins-Boaz B, Fortner K, Frazier J, Piluso S, Pullen S, Rasar M, Reid W, Sinclair K, Winger E: Oocyte maturation in Xenopus laevis is blocked by the hormonal herbicide, 2,4-dichlorophenoxy Mol Reprod Dev. 2004 Feb;67(2):233-42. However, Western blot analysis and U0126 inhibitor studies showed that 2,4-D, either alone or in the presence of induced MAPK phosphorylation through MAPKK. |
31(0,1,1,1) | Details |
| 17507104 | Liu PF, Chang WC, Wang YK, Munisamy SB, Hsu SH, Chang HY, Wu SH, Pan RL: Differential regulation of Ku gene expression in etiolated mung bean hypocotyls by auxins. Biochim Biophys Acta. 2007 Jul-Aug;1769(7-8):443-54. Epub 2007 Apr 10. Further analysis using specific inhibitors of auxin signaling showed that the stimulation of VrKu expression by 2,4-dichlorophenoxyacetic acid (2,4-D) was suppressed by intracellular Ca (2+) chelators, calmodulin antagonists, and /calmodulin dependent protein kinase inhibitors, suggesting the involvement of calmodulin in the signaling pathway. On the other hand, exogenous (IAA) and alpha-naphthalene (NAA) stimulated VrKu expression through the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway. |
1(0,0,0,1) | Details |
| 8130795 | Mizoguchi T, Gotoh Y, Nishida E, Yamaguchi-Shinozaki K, Hayashida N, Iwasaki T, Kamada H, Shinozaki K: Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Plant J. 1994 Jan;5(1):111-22. Two cDNA clones, cATMPK1 and cATMPK2, encoding MAP kinases (mitogen-activated protein kinases) have been cloned from Arabidopsis thaliana and their nucleotide sequences have been determined. A rapid and transient activation of 46-kDa protein kinase activity that phosphorylated myelin basic protein (MBP) was detected when auxin-starved tobacco BY-2 cells were treated with synthetic auxin, 2,4-dichlorophenoxyacetic acid (2,4-D). |
2(0,0,0,2) | Details |