Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
3972054 Bernard PA, Toyoshima E, Eccles CU, Mayer RF, Johnson KP, Max SR: 2,4-Dichlorophenoxyacetic acid (2,4-D) reduces acetylcholinesterase activity in rat muscle. Exp Neurol. 1985 Mar;87(3):544-56.
101(1,1,4,6) Details
17935783 da Fonseca MB, Glusczak L, Moraes BS, de Menezes CC, Pretto A, Tierno MA, Zanella R, Goncalves FF, Loro VL: The 2,4-D herbicide effects on acetylcholinesterase activity and metabolic parameters of piava freshwater fish (Leporinus obtusidens). Ecotoxicol Environ Saf. 2008 Mar;69(3):416-20. Epub 2007 Nov 1.
19(0,0,3,4) Details
8898484 Lakshmana MK, Raju TR: 2, 4-dichloro phenoxy acetic acid alters monoamine levels, acetylcholinesterase activity & operant learning in rats. Indian J Med Res. 1996 Sep;104:234-9.

2(0,0,0,2) Details
18383919 Siatka T, Kasparova M: Effects of auxins on growth and scopoletin accumulation in cell suspension cultures of Angelica archangelica L. Ceska Slov Farm. 2008 Jan;57(1):17-20.

Scopoletin is a coumarin possessing many interesting biological effects, e.g., spasmolytic, anti-inflammatory, antimutagenic, antioxidant, antifungal, apoptosis-inducing, antiproliferative, acetylcholinesterase-inhibitory, and hypouricemic activities.
Effects of four auxins (2,4-dichlorophenoxyacetic acid, 2,4-D, alpha-naphthaleneacetic acid, NAA, beta-indoleacetic acid, IAA or beta-indolebutyric acid, IBA) at four concentrations (0.2, 2, 10 or 20 mg/l) on the culture growth and accumulation of scopoletin in the medium were tested in Angelica archangelica cell suspension cultures cultured under continuous light or in the dark.
1(0,0,0,1) Details
1797200 Rodriguez EM, Monserrat JM: Acute and chronic effects of parathion and 2,4 D on the oxygen consumption of Chasmagnathus granulata (Decapoda, Brachyura). Acta Physiol Pharmacol Ther Latinoam. 1991;41(2):201-10.

Crabs exposed to parathion -an organophosphorate insecticide that causes the inhibition of acetylcholinesterase- show an increase of oxygen consumption at 0.5 ppm under acute exposure, and at 10 ppb under a chronic one.
1(0,0,0,1) Details