Protein Information

Name TPO1
Synonyms SERINC 5; SERINC5; TPO 1; TPO1; serine incorporator 5; serine incorporator 5s

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
11906193 Teixeira MC, Sa-Correia I: Saccharomyces cerevisiae resistance to chlorinated phenoxyacetic acid herbicides involves Pdr1p-mediated transcriptional activation of TPO1 and PDR5 genes. Biochem Biophys Res Commun. 2002 Mar 29;292(2):530-7.

A rapid and transient activation of TPO1 (sixfold) and PDR5 (twofold) transcription takes place during the adaptation period preceding cell division under MCPA or 2,4-D moderate stress.
34(0,1,1,4) Details
19440702 Cabrito TR, Teixeira MC, Duarte AA, Duque P, Sa-Correia I: Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast. Appl Microbiol Biotechnol. 2009 Oct;84(5):927-36. Epub 2009 May 14.

The TPO1 gene, encoding a multidrug resistance (MDR) plasma membrane transporter of the major facilitator superfamily (MFS), was previously found to confer resistance to 2,4-D in yeast and to be transcriptionally activated in response to the herbicide.
31(0,1,1,1) Details
16487346 Teixeira MC, Fernandes AR, Mira NP, Becker JD, Sa-Correia I: Early transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid. FEMS Yeast Res. 2006 Mar;6(2):230-48.


The global gene transcription pattern of the eukaryotic experimental model Saccharomyces cerevisiae in response to sudden aggression with the widely used herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) was analysed.
0(0,0,0,0) Details