| Name | acyl CoA dehydrogenase |
|---|---|
| Synonyms | short chain acyl coenzyme A dehydrogenase; ACAD 3; ACAD3; ACADS; Acyl CoA dehydrogenase; Acyl Coenzyme A dehydrogenase; Butyryl CoA dehydrogenase; Butyryl Coenzyme A dehydrogenase… |
| Name | MCPA |
|---|---|
| CAS | 2-(4-chloro-2-methylphenoxy)acetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1931995 | Tserng KY, Jin SJ, Hoppel CL: Spiropentaneacetic acid as a specific inhibitor of medium-chain acyl-CoA dehydrogenase. Biochemistry. 1991 Nov 5;30(44):10755-60. In contrast, MCPA inhibited both MCAD and short-chain acyl-CoA dehydrogenase with a stronger inhibition toward the latter. |
81(1,1,1,1) | Details |
| 9804184 | Broadway NM, Engel PC: Novel methylenecyclopropyl-based acyl-CoA dehydrogenase inhibitor. . FEBS Lett. 1998 Oct 16;437(1-2):122-6. SCAD and MCPA- inhibition was accompanied by flavin bleaching. |
34(0,1,1,4) | Details |
| 2331485 | Ikeda Y, Tanaka K: Selective inactivation of various acyl-CoA dehydrogenases by (methylenecyclopropyl) Biochim Biophys Acta. 1990 Apr 19;1038(2):216-21. Inactivation of five distinct acyl-CoA dehydrogenases by (methylenecyclopropyl) (MCPA- the toxic metabolite of hypoglycin from unripe ackee fruit, was investigated using purified enzyme preparations. |
32(0,1,1,2) | Details |
| 9124539 | Lieu YK, Hsu BY, Price WA, Corkey BE, Stanley CA: effects on profiles in rat liver with hypoglycin inhibition of multiple dehydrogenases. Am J Physiol. 1997 Mar;272(3 Pt 1):E359-66. To examine the changes in profile and the possible corrective effects of supplementation in the genetic disorders of mitochondrial beta-oxidation, we carried out experiments using an inhibitor of multiple acyl-CoA dehydrogenase enzymes, methylenecyclopropaneacetic acid (MCPA), in rat hepatocytes. |
31(0,1,1,1) | Details |