Protein Information

Name AHAS
Synonyms 209L8; AHAS; Acetolactate synthase; Acetolactate synthase homolog; ILV2H; ILVB like; ILVBL; IlvB (Bacterial acetolactate synthase) like isoform 1 variant…

Compound Information

Name imazethapyr
CAS

Reference List

PubMed Abstract RScore(About this table)
15627242 Tan S, Evans RR, Dahmer ML, Singh BK, Shaner DL: Imidazolinone-tolerant crops: history, current status and future. Pest Manag Sci. 2005 Mar;61(3):246-57.

Imidazolinone herbicides, which include imazapyr, imazapic, imazethapyr, imazamox, imazamethabenz and imazaquin, control weeds by inhibiting the enzyme acetohydroxyacid synthase (AHAS), also called acetolactate synthase (ALS).
85(1,1,1,5) Details
19495723 Laplante J, Rajcan I, Tardif FJ: Multiple allelic forms of acetohydroxyacid synthase are responsible for herbicide resistance in Setaria viridis. Theor Appl Genet. 2009 Aug;119(4):577-85. Epub 2009 Jun 4.

Five green foxtail [Setaria viridis (L.) Beauv.] populations were reported in Ontario with potential resistance to the AHAS-inhibiting herbicide imazethapyr.
84(1,1,1,4) Details
12590124 Ott KH, Aranibar N, Singh B, Stockton GW: Metabonomics classifies pathways affected by bioactive compounds. Phytochemistry. 2003 Mar;62(6):971-85.

Corn (Zea mays) plants were treated with various herbicides such as imazethapyr, glyphosate, sethoxydim, and diuron, which represent various biochemical modes-of-action such as inhibition of specific enzymes (acetohydroxy acid synthase [AHAS], protoporphyrin IX oxidase [PROTOX], 5-enolpyruvylshikimate-3-phosphate synthase [EPSPS], acetyl CoA carboxylase [ACC-ase], etc.), or protein complexes (photosystems I and II), or major biological process such as oxidative phosphorylation, auxin transport, microtubule growth, and mitosis.
81(1,1,1,1) Details
15309298 Kolkman JM, Slabaugh MB, Bruniard JM, Berry S, Bushman BS, Olungu C, Maes N, Abratti G, Zambelli A, Miller JF, Leon A, Knapp SJ: Acetohydroxyacid synthase mutations conferring resistance to imidazolinone or sulfonylurea herbicides in sunflower. Theor Appl Genet. 2004 Oct;109(6):1147-59. Epub 2004 Aug 10.

Biotypes resistant to two classes of AHAS-inhibiting herbicides-imidazolinones (IMIs) or sulfonylureas (SUs)-have been discovered in wild sunflower populations (ANN-PUR and ANN-KAN) treated with imazethapyr or chlorsulfuron, respectively.
35(0,1,1,5) Details
17910989 Fragiorge EJ, Rezende AA, Graf U, Spano MA: Comparative genotoxicity evaluation of imidazolinone herbicides in somatic cells of Drosophila melanogaster. Food Chem Toxicol. 2008 Jan;46(1):393-401. Epub 2007 Aug 24.

In the present study, five analogous herbicides, namely Imazapyr (IMZR), Imazapic (IMZC), Imazethapyr (IMZT), Imazamox (IMZX) and Imazaquin (IMZQ), were evaluated for genotoxicity (mutagenic and recombinagenic activity) in the wing somatic mutation and recombination test (SMART) of Drosophila melanogaster.
They are classified as imidazolinone (IMI) herbicides and their mode of action is to inhibit acetohydroxyacid synthase (AHAS), an enzyme involved in the biosynthesis of the amino acids leucine, isoleucine and valine.
1(0,0,0,1) Details