| Name | Cytochrome c oxidase (protein family or complex) |
|---|---|
| Synonyms | COX; cytochrome c oxidase; cytochrome c oxidases |
| Name | ferrous sulfate |
|---|---|
| CAS | sulfuric acid iron(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11511199 | Thrash TP, Wilson LJ: Zn (II), Ni (II), Cu (II), and Fe (III) complexes of potentially bimetalating tris - and -appended) picket-fence naphthylporphyrins with benzyl ether spacers: implications for cytochrome c oxidase active-site modeling. Inorg Chem. 2001 Aug 27;40(18):4556-62. An unusual monomeric iron (III) hydroxo complex was isolated upon workup of the compound formed under ferrous sulfate/ reflux conditions. |
2(0,0,0,2) | Details |
| 184977 | Blayney L, Bailey-Wood R, Jacobs A, Henderson A, Muir J: The effects of iron deficiency on the respiratory function and cytochrome content of rat heart mitochondria. Circ Res. 1976 Nov;39(5):744-8. Both groups received identical diet but an iron supplement (180 mg of ferrous sulfate per kg of diet) was added for the control group. Cytochrome c oxidase activity was significantly reduced only at 14 weeks as were the concentrations of cytochromes a3, c1, and b. |
1(0,0,0,1) | Details |
| 18685954 | Zhang Z, Lian B, Cui F: Effect of FeSO4 treatment on metabolism in diabetic rats. Biometals. 2008 Dec;21(6):685-91. Epub 2008 Aug 7. Kidney and liver tissues were excised at the end of the study for assaying enzymatic activities of isocitrate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, NADH-dehydrogenase and cytochrome-c-oxidase. |
1(0,0,0,1) | Details |
| 14622297 | You D, Ren X, Xue Y, Luo G, Yang T, Shen J: A -containing single-chain abzyme with potent antioxidant activity. Eur J Biochem. 2003 Nov;270(21):4326-31. To evaluate the antioxidant ability of Se-2F3-scFv, we constructed a ferrous sulfate/ (Vc/Fe2+)-induced mitochondrial damage model system and investigated the capacity of Se-2F3-scFv to protect mitochondria from oxidative damage. Se-2F3-scFv markedly decreased mitochondrial swelling, inhibited lipid peroxidation, and maintained the activity of cytochrome c oxidase, in comparison with Ebselen, a well-studied peroxidase mimic, indicating that Se-2F3-scFv has potential for treating diseases mediated by ROS. |
1(0,0,0,1) | Details |
| 9271239 | Foury F, Cazzalini O: Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria. FEBS Lett. 1997 Jul 14;411(2-3):373-7. Deletion of YDL120, the yeast homologue of the human gene responsible for Friedreich's ataxia, elicits decreased cellular respiration associated with decreased cytochrome c oxidase activity and, in certain nuclear backgrounds, mitochondrial DNA is lost. However, only ferrous sulfate elicits loss of mitochondrial DNA. |
1(0,0,0,1) | Details |
| 16258190 | Yu H, Liu J, Li J, Zang T, Luo G, Shen J: Protection of mitochondrial integrity from oxidative stress by -containing glutathione transferase. Appl Biochem Biotechnol. 2005 Nov;127(2):133-42. The antioxidant activity of a novel artificial peroxidase-like enzyme, -containing 5-transferase from Lucilia cuprina (seleno-LuGST1-1), was studied by using a ferrous sulfate/-induced mitochondrial damage model system. Swelling of mitochondria, lipid peroxidation, and cytochrome-c oxidase activity were selected to evaluate the preservation of mitochondrial integrity in this system. |
1(0,0,0,1) | Details |