| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | ferrous sulfate |
|---|---|
| CAS | sulfuric acid iron(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6835204 | Kloss MW, Rosen GM, Rauckman EJ: N-demethylation of cocaine to norcocaine. Mol Pharmacol. 1983 Mar;23(2):482-5. In addition, a model system consisting of ferrous sulfate was found to catalyze the N-demethylation of cocaine N-oxide. Evidence for participation by cytochrome P-450 and FAD-containing monooxygenase.. |
5(0,0,0,5) | Details |
| 19500726 | Liu Y, Pocivavsek A, Papadopoulos V: formation is independent of cytochrome P450 17alpha-hydroxylase/17, 20 lyase activity in the mouse brain. J Steroid Biochem Mol Biol. 2009 Jul;115(3-5):86-90. Epub 2009 Mar 27. |
2(0,0,0,2) | Details |
| 9371716 | Rota C, Barr DP, Martin MV, Guengerich FP, Tomasi A, Mason RP: Detection of free radicals produced from the reaction of cytochrome P-450 with hydroperoxide. Biochem J. 1997 Dec 1;328 ( Pt 2):565-71. |
2(0,0,0,2) | Details |
| 6882383 | Searle AJ, Willson RL: Stimulation of microsomal lipid peroxidation by iron and Biochem J. 1983 Jun 15;212(3):549-54. Stimulation of peroxidation was shown to be independent of microsomal protein, including cytochrome P-450. |
1(0,0,0,1) | Details |
| 18765684 | Sanderson JP, Hollis FJ, Maggs JL, Clarke SE, Naisbitt DJ, Park BK: Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites. Drug Metab Dispos. 2008 Dec;36(12):2424-8. Epub 2008 Sep 2. Partial inhibition of the aryl hydroxylation by 1-aminobenzotriazole suggested some involvement of cytochrome P450. |
1(0,0,0,1) | Details |
| 1651678 | Saad MJ, Morais SL, Saad ST: Reduced secretion in patients with iron deficiency. . Ann Nutr Metab. 1991;35(2):111-5. The iron-containing protein cytochrome P-450 is present in high concentration in the adrenal cortex and is involved in the synthesis of The same test was performed in 6 patients with iron deficiency, 7 days after therapy with 800 mg of ferrous sulfate. |
1(0,0,0,1) | Details |
| 6409153 | Brogan WC 3rd, Miles PR, Colby HD: Effects of lipid peroxidation on microsomal monooxygenases. . Biochim Biophys Acta. 1983 Jul 29;758(2):114-20. In addition, cytochrome P-450 levels, - and -cytochrome c reductase activities, and substrate interactions with cytochrome (s) P-450 decreased as lipid peroxidation progressed. |
1(0,0,0,1) | Details |
| 12493551 | Brown RC, Han Z, Cascio C, Papadopoulos V: Oxidative stress-mediated formation in Alzheimer's disease pathology. Neurobiol Aging. 2003 Jan-Feb;24(1):57-65. An alternative pathway for synthesis has been suggested by treating rat and human brain cells with ferrous sulfate and beta-amyloid (Abeta). |
0(0,0,0,0) | Details |