| 6421970 |
Rosenmund A, Haeberli A, Straub PW: Blood coagulation and acute iron toxicity. J Lab Clin Med. 1984 Apr;103(4):524-33.
Because the amidolytic activity of human thrombin as well as factor Xa, kallikrein, and bovine trypsin was also reversibly suppressed by ferrous sulfate as well as ferric citrate, we consider it likely that the coagulopathy occurring in iron poisoning is the consequence of a general, physiologically important phenomenon: the susceptibility of serine proteases to nontransferrin-bound Fe3+. |
81(1,1,1,1) |
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