Protein Information

Name sphingomyelinase
Synonyms CBP; CBP; Csk binding protein; PAG; PAG 1; PAG1; Phosphoprotein associated with glycosphingolipid enriched microdomains; Phosphoprotein associated with glycosphingolipid enriched microdomains 1…

Compound Information

Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
10770967 Zager RA, Burkhart KM, Johnson A: Sphingomyelinase and membrane sphingomyelin content: determinants ofProximal tubule cell susceptibility to injury. J Am Soc Nephrol. 2000 May;11(5):894-902.

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9727376 Zager RA, Conrad DS, Burkhart K: Ceramide accumulation during oxidant renal tubular injury: mechanisms and potential consequences. J Am Soc Nephrol. 1998 Sep;9(9):1670-80.


Ceramide is an important signaling molecule that is typically generated via sphingomyelinase (SMase)-mediated sphingomyelin (SM) hydrolysis.
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