Protein Information

Name interleukin 1 beta
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
10444519 Smirnov IM, Bailey K, Flowers CH, Garrigues NW, Wesselius LJ: Effects of TNF-alpha and IL-1beta on iron metabolism by A549 cells and influence on cytotoxicity. Am J Physiol. 1999 Aug;277(2 Pt 1):L257-63.

6(0,0,0,6) Details
1988302 Uchida T, Yamagiwa A, Nakamura K: The effect of interleukin-1 on iron metabolism in rats. Eur J Haematol. 1991 Jan;46(1):1-5.

Although the percent of radioactivity in plasma of the total injected dose was 3.2 +/- 0.6% in interleukin-1, which was significantly lower than in the control rats (5.4 +/- 0.6%) at 9 h after intravenous injection of 59Fe chondroitin ferrous sulfate, there was no difference between the amount of 59Fe released from the mononuclear phagocyte system over the first 9 h in interleukin-1 and control rats.
5(0,0,0,5) Details
16786194 Campo GM, Avenoso A, Campo S, Angela D, Ferlazzo AM, Calatroni A: TNF-alpha, IFN-gamma, and IL-1beta modulate hyaluronan synthase expression in human skin fibroblasts: synergistic effect by concomital treatment with FeSO4 plus ascorbate. Mol Cell Biochem. 2006 Nov;292(1-2):169-78. Epub 2006 Jun 20.

4(0,0,0,4) Details
7840815 Fuhrman B, Oiknine J, Aviram M: Iron induces lipid peroxidation in cultured macrophages, increases their ability to oxidatively modify LDL, and affects their secretory properties. Atherosclerosis. 1994 Nov;111(1):65-78.


Macrophage lipid peroxidation increases cell-mediated oxidation of LDL, enhances the release of interleukin 1 and inhibits the release of apolipoprotein E from the macrophages.
2(0,0,0,2) Details
7841356 Munoz C, Olivares M, Schlesinger L, Lopez M, Letelier A: Increased in vitro tumour necrosis factor-alpha production in iron deficiency anemia. Eur Cytokine Netw. 1994 Jul-Aug;5(4):401-4.


In vitro monocyte-derived tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) production was assessed in iron deficient with anemia (IDA), iron deficient without anemia (ID) and control infants.
1(0,0,0,1) Details