Protein Information

Name kinesin
Synonyms KIF5C; KIF5A; NKHC; KINN; Kinesin family member 5C; Kinesin heavy chain isoform 5C; Kinesin heavy chain neuron specific 2; NKHC 2…

Compound Information

Name sulfuric acid
CAS sulfuric acid

Reference List

PubMed Abstract RScore(About this table)
18539120 Dictenberg JB, Swanger SA, Antar LN, Singer RH, Bassell GJ: A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell. 2008 Jun;14(6):926-39.


Motor-dependent translocation of FMRP and cognate mRNAs involved the C terminus of FMRP and kinesin light chain, and KO brain showed reduced kinesin-associated mRNAs.
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12175672 Holzinger A, Lutz-Meindl U: Kinesin-like proteins are involved in postmitotic nuclear migration of the unicellular green alga Micrasterias denticulata. Cell Biol Int. 2002;26(8):689-97.

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17176086 Brier S, Carletti E, DeBonis S, Hewat E, Lemaire D, Kozielski F: The marine natural product adociasulfate-2 as a tool to identify the MT-binding region of kinesins. Biochemistry. 2006 Dec 26;45(51):15644-53. Epub 2006 Dec 1.


We have used the marine natural product adociasulfate-2 (AS-2), previously identified as a MT-competitive inhibitor of conventional kinesin, to infer the secondary structure elements forming the MT interface of two human mitotic kinesins, namely, CENP-E and Eg5.
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16884297 Reddie KG, Roberts DR, Dore TM: Inhibition of kinesin motor proteins by adociasulfate-2. J Med Chem. 2006 Aug 10;49(16):4857-60.


Inhibitors of kinesin would be valuable as probes of cell physiology and as potential therapeutics.
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