| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | sulfuric acid |
|---|---|
| CAS | sulfuric acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17220239 | Vincent SH, Reed JR, Bergman AJ, Elmore CS, Zhu B, Xu S, Ebel D, Larson P, Zeng W, Chen L, Dilzer S, Lasseter K, Gottesdiener K, Wagner JA, Herman GA: Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C] sitagliptin in humans. Drug Metab Dispos. 2007 Apr;35(4):533-8. Epub 2007 Jan 12. CYP3A4 was the major cytochrome P450 isozyme responsible for the limited oxidative metabolism of sitagliptin, with some minor contribution from CYP2C8. |
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| 11950790 | Otake Y, Hsieh F, Walle T: Glucuronidation versus oxidation of the galangin by human liver microsomes and hepatocytes. Drug Metab Dispos. 2002 May;30(5):576-81. In a previous study, we used human liver microsomes for the first time to study cytochrome P450 (P450)-mediated oxidation of the galangin. |
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| 16035375 | Fuhr U, Kober S, Zaigler M, Mutschler E, Spahn-Langguth H: Rate-limiting biotransformation of is mediated by CYP1A2. . Int J Clin Pharmacol Ther. 2005 Jul;43(7):327-34. To identify the cytochrome P450 enzyme (s) catalyzing hydroxylation of (the rate-limiting step in the formation of the ester (STA)), in vitro incubation studies were performed with human liver microsomes. |
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| 17315539 | Wu WN, McKown LA, Reitz AB: Metabolism of the new anxiolytic agent, a pyrido [1,2-] benzimidazole (PBI) analog (RWJ-53050), in rat and human hepatic S9 fractions, and in dog; identification of cytochrome p450 isoforms mediated in the human microsomal metabolism. Eur J Drug Metab Pharmacokinet. 2006 Oct-Dec;31(4):277-83. |
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