| Name | transthyretin |
|---|---|
| Synonyms | ATTR; HsT2651; PALB; Prealbumin; TBPA; TTR; Transthyretin; Transthyretin precursor… |
| Name | sulfuric acid |
|---|---|
| CAS | sulfuric acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18441837 | Suzuki G, Takigami H, Watanabe M, Takahashi S, Nose K, Asari M, Sakai S: Identification of brominated and chlorinated phenols as potential thyroid-disrupting compounds in indoor dusts. Environ Sci Technol. 2008 Mar 1;42(5):1794-800. Our previous study demonstrated that compounds in indoor dusts strongly inhibit (T4) binding to the human thyroid hormone transport protein transthyretin (TTR) in vitro. Here, we used chemical fractionation with in vitro competitive human TTR-binding assay and GC-MS to analyze the TTR-binding compounds in a sulfuric-acid-treated dust extract. 2,4,6-Tribromophenol (TriBPh) and 2,3,4,5,6-pentachlorophenol (PeCPh) were potent TTR-binding compounds in all dust samples. 2,4,6-TriBPh- and 2,3,4,5,6-PeCPh-derived theoretical T4 equivalents (T4EQs), calculated arithmetically from the concentrations and relative potencies, accounted for about 40-70% of experimental T4EQs detected in indoor dusts, indicating that these compounds contributed strongly to the TTR-binding potency of indoor dust. |
1(0,0,0,1) | Details |
| 17593761 | Suzuki G, Takigami H, Nose K, Takahashi S, Asari M, Sakai S: Dioxin-like and transthyretin-binding compounds in indoor dusts collected from Japan: average daily dose and possible implications for children. Environ Sci Technol. 2007 Feb 15;41(4):1487-93. Dioxin-like and TTR-binding activities in sulfuric acid treatment extracts of house and office dust were investigated using Dioxin-Responsive Chemical-Activated LUciferase gene eXpression assay (DR-CALUX) and TTR-binding assay (in vitro competitive human TTR-binding assay). |
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| 17063874 | Shimizu A: [Analysis of variant and modified structures of proteins by mass spectrometry--application for clinical laboratory test]. Rinsho Byori. 2006 Sep;54(9):924-34. The article addresses the detection and characterization of hemoglobin (Hb) variants, an improved reference method for HbAlc measurement, identification of variants of transthyretin (TTR) and Cu/Zn-superoxide dismutase (SOD-1) and the diagnostic application of the signals of modified forms of TTR. Without the addition of sulfuric acid, the S-sulfonated adduct was generated, namely, was generated from the peptide or protein itself via dimer formation. |
1(0,0,0,1) | Details |