Protein Information

Name activated protein C
Synonyms APC; Activated protein C; Activated protein C cofactor; Coagulation factor V; Coagulation factor V precursor; F5; FVL; Factor V…

Compound Information

Name DMPA
CAS

Reference List

PubMed Abstract RScore(About this table)
11920229 Mercier E, Branger B, Vecina F, Al-Sabadani B, Berlan J, Dauzat M, Fourcade J, Gris JC: Tissue factor coagulation pathway and blood cells activation state in renal insufficiency. Hematol J. 2001;2(1):18-25.

We studied basal plasma concentrations of FVIIa, factor VII-related antigen (FVIIAg), soluble TF, tissue factor pathway inhibitor (TFPI), TF-dependent circulating monocytes procoagulant activity (TF-dMPA), tissue factor-dependent plasma reactivity to activated protein C (TF-aPC), D-dimers (D-Di), and circulating markers of cellular activation/injury: soluble thrombomodulin (sTM), circulating microparticles (microP), soluble leukocyte, endothelial and platelet selectins (sL-selectin, sE-selectin, sP-selectin), soluble intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 (sICAM-1 and sVCAM-1).
32(0,1,1,2) Details
17336967 Goldstein J, Cushman M, Badger GJ, Johnson JV: Effect of depomedroxyprogesterone acetate on coagulation parameter: a pilot study. Fertil Steril. 2007 Jun;87(6):1267-70. Epub 2007 Mar 6.

To investigate this, we studied the effects of injectable depomedroxyprogesterone acetate (DMPA), given as a contraceptive, on coagulation and inflammation markers.
MAIN OUTCOME MEASURE (S): D-Dimer, C-reactive protein (CRP), antithrombin (AT), factor VIIIc, activated partial thromboplastin time (aPTT), and aPTT plus activated protein C (APC) were analyzed on all samples.
1(0,0,0,1) Details